"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor ID |
D013569
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MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
1999 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2016 | 2 | 1 | 3 |
2017 | 11 | 7 | 18 |
2018 | 6 | 8 | 14 |
2019 | 0 | 2 | 2 |
2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics. Pharmacol Rev. 2021 04; 73(2):792-827.
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Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations. J Mol Neurosci. 2021 Nov; 71(11):2192-2209.
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ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. Cell Stem Cell. 2021 02 04; 28(2):331-342.e5.
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Potential Novel Role of COVID-19 in Alzheimer's Disease and Preventative Mitigation Strategies. J Alzheimers Dis. 2020; 76(1):21-25.
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Hydrogen sulfide ameliorates disorders in the parafacial respiratory group region of neonatal rats caused by prenatal cigarette smoke exposure via an antioxidative effect. Environ Toxicol Pharmacol. 2019 May; 68:80-90.
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Photobiomodulation preconditioning prevents cognitive impairment in a neonatal rat model of hypoxia-ischemia. J Biophotonics. 2019 06; 12(6):e201800359.
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Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain. Nat Commun. 2018 11 19; 9(1):4879.
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The importance of recurrent top-down synaptic connections for the anticipation of dynamic emotions. Neural Netw. 2019 Jan; 109:19-30.
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Multiple sclerosis and cognition: synaptic failure and network dysfunction. Nat Rev Neurosci. 2018 10; 19(10):599-609.
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Fast regular firings induced by intra- and inter-time delays in two clustered neuronal networks. Chaos. 2018 Oct; 28(10):106310.