"RNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that promote unwinding of RNA during splicing and translation.
| Descriptor ID |
D020365
|
| MeSH Number(s) |
D08.811.913.696.445.735.720
|
| Concept/Terms |
RNA Helicases- RNA Helicases
- Helicases, RNA
- RNA Helicase
- Helicase, RNA
|
Below are MeSH descriptors whose meaning is more general than "RNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "RNA Helicases".
This graph shows the total number of publications written about "RNA Helicases" by people in this website by year, and whether "RNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 4 | 9 | 13 |
| 2018 | 4 | 4 | 8 |
| 2019 | 1 | 3 | 4 |
| 2020 | 5 | 3 | 8 |
| 2021 | 4 | 3 | 7 |
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Below are the most recent publications written about "RNA Helicases" by people in Profiles.
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Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun. 2021 08 11; 12(1):4848.
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Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase. J Phys Chem B. 2021 08 12; 125(31):8787-8796.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase. Biochem J. 2021 07 16; 478(13):2405-2423.
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ddPCR increases detection of SARS-CoV-2 RNA in patients with low viral loads. Arch Virol. 2021 Sep; 166(9):2529-2540.
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High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses. Molecules. 2021 Jun 22; 26(13).
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Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets. Science. 2021 07 09; 373(6551):236-241.
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Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase. Sci Rep. 2021 05 13; 11(1):10290.
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Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc Natl Acad Sci U S A. 2021 05 11; 118(19).
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Coronavirus helicases: attractive and unique targets of antiviral drug-development and therapeutic patents. Expert Opin Ther Pat. 2021 Apr; 31(4):339-350.
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Molecular epidemiology analysis of early variants of SARS-CoV-2 reveals the potential impact of mutations P504L and Y541C (NSP13) in the clinical COVID-19 outcomes. Infect Genet Evol. 2021 08; 92:104831.