Nucleoside-Triphosphatase
"Nucleoside-Triphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of nucleoside triphosphates to nucleoside diphosphates. It may also catalyze the hydrolysis of nucleotide triphosphates, diphosphates, thiamine diphosphates and FAD. The nucleoside triphosphate phosphohydrolases I and II are subtypes of the enzyme which are found mostly in viruses.
| Descriptor ID |
D043583
|
| MeSH Number(s) |
D08.811.277.040.465
|
| Concept/Terms |
Nucleoside-Triphosphatase- Nucleoside-Triphosphatase
- Nucleosidetriphosphatase
- Nucleoside Triphosphate Phosphohydrolase
- Phosphohydrolase, Nucleoside Triphosphate
- Triphosphate Phosphohydrolase, Nucleoside
- NTPase
- Nucleoside Triphosphatase
- Triphosphatase, Nucleoside
|
Below are MeSH descriptors whose meaning is more general than "Nucleoside-Triphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Nucleoside-Triphosphatase".
This graph shows the total number of publications written about "Nucleoside-Triphosphatase" by people in this website by year, and whether "Nucleoside-Triphosphatase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Nucleoside-Triphosphatase" by people in Profiles.
-
SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts. Virol Sin. 2020 Jun; 35(3):321-329.
-
Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities. J Virol. 2018 03 01; 92(5).
-
Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target. Biochem Pharmacol. 2012 Nov 15; 84(10):1351-8.
-
Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase. Bioorg Med Chem Lett. 2009 Mar 15; 19(6):1636-8.
-
Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase. Biochem Biophys Res Commun. 2008 Feb 15; 366(3):738-44.
-
Antivirals and antiviral strategies. Nat Rev Microbiol. 2004 Sep; 2(9):704-20.
-
Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5'-triphosphatase activities. J Virol. 2004 Jul; 78(14):7833-8.
-
The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases. J Biol Chem. 2003 Oct 10; 278(41):39578-82.
-
Guanosine triphosphatase activity of the human coronavirus helicase. Adv Exp Med Biol. 2001; 494:255-60.