"Polymyxin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
| Descriptor ID |
D011112
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| MeSH Number(s) |
D04.345.566.780.750 D10.477.750.750 D12.644.050.600.750 D12.644.641.780.750 D12.776.543.695.054.600.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Polymyxin B".
Below are MeSH descriptors whose meaning is more specific than "Polymyxin B".
This graph shows the total number of publications written about "Polymyxin B" by people in this website by year, and whether "Polymyxin B" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 4 | 7 |
| 2018 | 7 | 2 | 9 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Polymyxin B" by people in Profiles.
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Possibility of PMX-DHP therapy as a principal strategy against cytokine storm in COVID-19: Insights from reconstructed coagulation data. J Clin Apher. 2021 Oct; 36(5):785-786.
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Endotoxin Adsorbent Therapy in Severe COVID-19 Pneumonia. Blood Purif. 2022; 51(1):47-54.
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Therapeutic Rationale for Endotoxin Removal with Polymyxin B Immobilized Fiber Column (PMX) for Septic Shock. Int J Mol Sci. 2021 Feb 23; 22(4).
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Polymyxin B hemoperfusion in coronavirus disease 2019 patients with endotoxic shock: Case series from EUPHAS2 registry. Artif Organs. 2021 Jun; 45(6):E187-E194.
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Direct hemoperfusion using a polymyxin B-immobilized polystyrene column for COVID-19. J Clin Apher. 2021 Jun; 36(3):313-321.
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Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion. Intern Med. 2020 Oct 01; 59(19):2405-2408.
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Synergistic effect of silver nanoparticles and polymyxin B against biofilm produced by Pseudomonas aeruginosa isolates of pus samples in vitro. Artif Cells Nanomed Biotechnol. 2019 Dec; 47(1):2465-2472.
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Endotoxin removal by polymyxin B: is it a question of dose or duration or both? Crit Care. 2019 09 04; 23(1):297.
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Risk factors and outcomes associated with the isolation of polymyxin B and carbapenem-resistant Enterobacteriaceae spp.: A case-control study. Int J Antimicrob Agents. 2019 May; 53(5):657-662.
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Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial. JAMA. 2018 10 09; 320(14):1455-1463.