"Sertoli Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
| Descriptor ID |
D012708
|
| MeSH Number(s) |
A05.360.444.849.789 A11.382.952 A11.436.837
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sertoli Cells".
Below are MeSH descriptors whose meaning is more specific than "Sertoli Cells".
This graph shows the total number of publications written about "Sertoli Cells" by people in this website by year, and whether "Sertoli Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Sertoli Cells" by people in Profiles.
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COVID-19 disrupts the blood-testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins. Inflamm Res. 2021 Dec; 70(10-12):1165-1175.
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Review of Sertoli cell dysfunction caused by COVID-19 that could affect male fertility. Zygote. 2022 Feb; 30(1):17-24.
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COVID-19 in men: With or without virus in semen, spermatogenesis may be impaired. Andrologia. 2021 02; 53(1):e13878.
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The ACE2 expression in Sertoli cells and germ cells may cause male reproductive disorder after SARS-CoV-2 infection. J Cell Mol Med. 2020 08; 24(16):9472-9477.
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Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications. Eur Urol Focus. 2020 Sep 15; 6(5):1124-1129.
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Could COVID-19 have an impact on male fertility? Andrologia. 2020 Jul; 52(6):e13654.
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Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes. Sci China Life Sci. 2020 07; 63(7):1006-1015.
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Immunoprofiles of human Sertoli cells infected with Zika virus reveals unique insights into host-pathogen crosstalk. Sci Rep. 2018 06 07; 8(1):8702.
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Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model. J Virol. 2017 11 15; 91(22).
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C-X-C motif chemokine ligand 10 produced by mouse Sertoli cells in response to mumps virus infection induces male germ cell apoptosis. Cell Death Dis. 2017 10 26; 8(10):e3146.