"Histone Deacetylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
Descriptor ID |
D006655
|
MeSH Number(s) |
D08.811.277.087.520
|
Concept/Terms |
Histone Deacetylases- Histone Deacetylases
- Deacetylases, Histone
- Histone Deacetylase
- Deacetylase, Histone
- HDAC Proteins
|
Below are MeSH descriptors whose meaning is more general than "Histone Deacetylases".
Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylases".
This graph shows the total number of publications written about "Histone Deacetylases" by people in this website by year, and whether "Histone Deacetylases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2010 | 2 | 0 | 2 |
2013 | 0 | 1 | 1 |
2017 | 7 | 6 | 13 |
2018 | 5 | 3 | 8 |
2019 | 5 | 1 | 6 |
2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Histone Deacetylases" by people in Profiles.
-
[Coronavirus disease (COVID-19) and sirtuins]. Rev Fac Cien Med Univ Nac Cordoba. 2020 06 16; 77(2):117-125.
-
Histone Deacetylases (HDACs) in Gastric Cancer: An Update of their Emerging Prognostic and Therapeutic Role. Curr Med Chem. 2020; 27(36):6099-6111.
-
MicroRNA-383-5p inhibits the progression of gastric carcinoma via targeting HDAC9 expression. Braz J Med Biol Res. 2019; 52(8):e8341.
-
Blocking histone deacetylase activity as a novel target for epithelial barrier defects in patients with allergic rhinitis. J Allergy Clin Immunol. 2019 11; 144(5):1242-1253.e7.
-
Epigenetic Modifications in Placenta are Associated with the Child's Sensitization to Allergens. Biomed Res Int. 2019; 2019:1315257.
-
HDAC4 mutations cause diabetes and induce ß-cell FoxO1 nuclear exclusion. Mol Genet Genomic Med. 2019 05; 7(5):e602.
-
Spatiotemporal chromatin dynamics - A telltale of circadian epigenetic gene regulation. Life Sci. 2019 Mar 15; 221:377-391.
-
Modeling Cornelia de Lange syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation. Hum Mol Genet. 2019 01 01; 28(1):64-73.
-
Aberrant histone modification and inflammatory cytokine production of peripheral CD4+ T cells in patients with oral lichen planus. J Oral Pathol Med. 2019 Feb; 48(2):136-142.
-
Concept of histone deacetylases in cancer: Reflections on esophageal carcinogenesis and treatment. World J Gastroenterol. 2018 Nov 07; 24(41):4635-4642.