"Tacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
| Descriptor ID |
D013619
|
| MeSH Number(s) |
D03.633.300.046.250.900
|
| Concept/Terms |
Tacrine- Tacrine
- 9-Amino-1,2,3,4-Tetrahydroacridine
- 1,2,3,4-Tetrahydro-9-acridinamine
- Tetrahydroaminoacridine
- 1,2,3,4-Tetrahydroaminoacridine
|
Below are MeSH descriptors whose meaning is more general than "Tacrine".
Below are MeSH descriptors whose meaning is more specific than "Tacrine".
This graph shows the total number of publications written about "Tacrine" by people in this website by year, and whether "Tacrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tacrine" by people in Profiles.
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Computational approach to suggest a new multi-target-directed ligand as a potential medication for Alzheimer's disease. J Biomol Struct Dyn. 2019 11; 37(18):4825-4839.
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Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning. Curr Pharm Des. 2019; 25(33):3519-3535.
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Large-scale in silico identification of drugs exerting sex-specific effects in the heart. J Transl Med. 2018 08 29; 16(1):236.