"HLA-A Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.
| Descriptor ID |
D015234
|
| MeSH Number(s) |
D12.776.395.550.489.400 D12.776.543.550.439.400 D23.050.301.500.100.400 D23.050.301.500.450.370 D23.050.705.552.100.400 D23.050.705.552.450.370
|
| Concept/Terms |
HLA-A Antigens- HLA-A Antigens
- HLA A Antigens
- HLA-A
- Antigens, HLA-A
- Antigens, HLA A
|
Below are MeSH descriptors whose meaning is more general than "HLA-A Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-A Antigens".
This graph shows the total number of publications written about "HLA-A Antigens" by people in this website by year, and whether "HLA-A Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2017 | 7 | 7 | 14 |
| 2018 | 3 | 1 | 4 |
| 2019 | 6 | 1 | 7 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "HLA-A Antigens" by people in Profiles.
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HLA genetic polymorphism in patients with Coronavirus Disease 2019 in Midwestern United States. HLA. 2021 10; 98(4):370-379.
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HLA-A homozygosis is associated with susceptibility to COVID-19. HLA. 2021 08; 98(2):122-131.
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Association between the HLA genotype and the severity of COVID-19 infection among South Asians. J Med Virol. 2021 07; 93(7):4430-4437.
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SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses. Sci Immunol. 2021 03 04; 6(57).
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Association of HLA Class I Genotypes With Severity of Coronavirus Disease-19. Front Immunol. 2021; 12:641900.
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Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19. Front Immunol. 2020; 11:565730.
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T and B cell Epitope analysis of SARS-CoV-2 S protein based on immunoinformatics and experimental research. J Cell Mol Med. 2021 01; 25(2):1274-1289.
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COVID-19 coronavirus vaccine T cell epitope prediction analysis based on distributions of HLA class I loci (HLA-A, -B, -C) across global populations. Hum Vaccin Immunother. 2021 04 03; 17(4):1097-1108.
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Association between HLA gene polymorphisms and mortality of COVID-19: An in silico analysis. Immun Inflamm Dis. 2020 12; 8(4):684-694.
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NCAM protein and SARS-COV-2 surface proteins: In-silico hypothetical evidence for the immunopathogenesis of Guillain-Barré syndrome. Med Hypotheses. 2020 Dec; 145:110342.