"Guanidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
| Descriptor ID |
D019791
|
| MeSH Number(s) |
D02.078.370.472
|
| Concept/Terms |
Guanidine Hydrochloride- Guanidine Hydrochloride
- Hydrochloride, Guanidine
- Guanidinium Chloride
- Chloride, Guanidinium
- Guanidium Chloride
- Chloride, Guanidium
- Guanidine Monohydrochloride
- Monohydrochloride, Guanidine
|
Below are MeSH descriptors whose meaning is more general than "Guanidine".
Below are MeSH descriptors whose meaning is more specific than "Guanidine".
This graph shows the total number of publications written about "Guanidine" by people in this website by year, and whether "Guanidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 2 | 5 | 7 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanidine" by people in Profiles.
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Inactivation of SARS-CoV-2 virus in saliva using a guanidium based transport medium suitable for RT-PCR diagnostic assays. PLoS One. 2021; 16(6):e0252687.
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Filling in the Gaps in Metformin Biodegradation: a New Enzyme and a Metabolic Pathway for Guanylurea. Appl Environ Microbiol. 2021 05 11; 87(11).
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Enhancing colorimetric loop-mediated isothermal amplification speed and sensitivity with guanidine chloride. Biotechniques. 2020 09; 69(3):178-185.
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Potential False-Negative Nucleic Acid Testing Results for Severe Acute Respiratory Syndrome Coronavirus 2 from Thermal Inactivation of Samples with Low Viral Loads. Clin Chem. 2020 06 01; 66(6):794-801.
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Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach. Chemosphere. 2019 Nov; 234:139-147.
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Investigation of the role of central metal ion of Cyathus bulleri laccase 1 using guanidinium chloride-induced denaturation. Int J Biol Macromol. 2019 Jul 01; 132:994-1000.
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Protein folding: Molecular dynamics simulations and in vitro studies for probing mechanism of urea- and guanidinium chloride-induced unfolding of horse cytochrome-c. Int J Biol Macromol. 2019 Feb 01; 122:695-704.
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Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation. Int J Biol Macromol. 2018 Oct 01; 117:1252-1263.
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Evidence for the involvement of TNF-a, IL-1ß and IL-10 in the antinociceptive and anti-inflammatory effects of indole-3-guanylhydrazone hydrochloride, an aromatic aminoguanidine, in rodents. Chem Biol Interact. 2018 Apr 25; 286:1-10.
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Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities. J Virol. 2018 03 01; 92(5).