Proto-Oncogene Proteins c-raf
"Proto-Oncogene Proteins c-raf" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
| Descriptor ID |
D019908
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| MeSH Number(s) |
D08.811.913.696.620.682.700.559.842.500 D12.644.360.400.842.500 D12.776.476.400.842.500 D12.776.624.664.700.204.500
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| Concept/Terms |
Proto-Oncogene Proteins c-raf- Proto-Oncogene Proteins c-raf
- Proteins c-raf, Proto-Oncogene
- Proto Oncogene Proteins c raf
- c-raf, Proto-Oncogene Proteins
- Proto-Oncogene Protein c-raf
- Protein c-raf, Proto-Oncogene
- Proto Oncogene Protein c raf
- c-raf, Proto-Oncogene Protein
- c-raf Kinases
- Kinases, c-raf
- c raf Kinases
- Kinase Raf-1
- Kinase Raf 1
- Raf-1, Kinase
- cRaf1 Kinase
- Kinase, cRaf1
- raf-1 Kinase
- Kinase, raf-1
- raf 1 Kinase
- c-raf Proteins
- Proteins, c-raf
- c raf Proteins
- Kinase p74(raf-1)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-raf".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-raf".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-raf" by people in this website by year, and whether "Proto-Oncogene Proteins c-raf" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-raf" by people in Profiles.
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Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies. Sci Rep. 2018 02 05; 8(1):2421.
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w09, a novel autophagy enhancer, induces autophagy-dependent cell apoptosis via activation of the EGFR-mediated RAS-RAF1-MAP2K-MAPK1/3 pathway. Autophagy. 2017 Jul 03; 13(7):1093-1112.
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Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf. Oncotarget. 2017 Apr 11; 8(15):25289-25299.
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Hepatitis B virus regulates Raf1 expression in HepG2.2.15 cells by enhancing its promoter activity. Arch Virol. 2011 May; 156(5):869-74.
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Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors. Cancer Res. 2003 Dec 01; 63(23):8132-7.