Endoplasmic Reticulum-Associated Degradation
"Endoplasmic Reticulum-Associated Degradation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
| Descriptor ID |
D060746
|
| MeSH Number(s) |
G02.111.660.871.790.600.962.500 G02.111.691.600.850.500 G03.734.871.790.600.850.500 G05.308.670.600.850.500
|
| Concept/Terms |
Endoplasmic Reticulum-Associated Degradation- Endoplasmic Reticulum-Associated Degradation
- Degradation, Endoplasmic Reticulum-Associated
- Endoplasmic Reticulum Associated Degradation
- Reticulum-Associated Degradation, Endoplasmic
- ERAD Pathway
- ERAD Pathways
- Pathway, ERAD
- Pathways, ERAD
|
Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum-Associated Degradation".
Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum-Associated Degradation".
This graph shows the total number of publications written about "Endoplasmic Reticulum-Associated Degradation" by people in this website by year, and whether "Endoplasmic Reticulum-Associated Degradation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Endoplasmic Reticulum-Associated Degradation" by people in Profiles.
-
Coronaviruses construct an interconnection way with ERAD and autophagy. Future Microbiol. 2021 09; 16:1135-1151.
-
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs. Mol Cell Proteomics. 2021; 20:100120.
-
Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects. J Exp Med. 2017 Dec 04; 214(12):3707-3729.
-
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication. PLoS Pathog. 2017 Oct; 13(10):e1006674.
-
Coronavirus-induced ER stress response and its involvement in regulation of coronavirus-host interactions. Virus Res. 2014 Dec 19; 194:110-23.
-
Unconventional roles of nonlipidated LC3 in ERAD tuning and coronavirus infection. Autophagy. 2012 Oct; 8(10):1534-6.
-
Role of the SEL1L:LC3-I complex as an ERAD tuning receptor in the mammalian ER. Mol Cell. 2012 Jun 29; 46(6):809-19.
-
Unconventional use of LC3 by coronaviruses through the alleged subversion of the ERAD tuning pathway. Viruses. 2011 09; 3(9):1610-23.