"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Descriptor ID |
D020442
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MeSH Number(s) |
D02.033.455.250.700.682 D05.750.741.667 D25.720.741.667 J01.637.051.720.741.667
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Poloxamer".
Below are MeSH descriptors whose meaning is more specific than "Poloxamer".
This graph shows the total number of publications written about "Poloxamer" by people in this website by year, and whether "Poloxamer" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2017 | 2 | 1 | 3 |
2018 | 0 | 3 | 3 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Poloxamer" by people in Profiles.
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Heparin-poloxamer hydrogel-encapsulated rhFGF21 enhances wound healing in diabetic mice. FASEB J. 2019 09; 33(9):9858-9870.
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Grade 3 anaphylactic shock after administration of [99mTc]-labeled nanocolloidal albumin (Nanocoll®) for sentinel node scintigraphy. Eur J Nucl Med Mol Imaging. 2019 Jun; 46(6):1214-1215.
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Preparation of Ibuprofen Microparticles by Antisolvent Precipitation Crystallization Technique: Characterization, Formulation, and In Vitro Performance. J Pharm Sci. 2018 12; 107(12):3060-3069.
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Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats. Biomaterials. 2018 06; 168:24-37.
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Dual-responsive lidocaine in situ gel reduces pain of intrauterine device insertion. Int J Pharm. 2018 Mar 01; 538(1-2):279-286.
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P-407-induced Mouse Model of Dose-controlled Hyperlipidemia and Atherosclerosis: 25 Years Later. J Cardiovasc Pharmacol. 2017 Nov; 70(5):339-352.
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Chitosan conduits filled with simvastatin/Pluronic F-127 hydrogel promote peripheral nerve regeneration in rats. J Biomed Mater Res B Appl Biomater. 2018 02; 106(2):787-799.
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A Thermosensitive Heparin-Poloxamer Hydrogel Bridges aFGF to Treat Spinal Cord Injury. ACS Appl Mater Interfaces. 2017 Mar 01; 9(8):6725-6745.
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Synthesis and characterization of Poloxamer 188-grafted heparin copolymer. Drug Dev Ind Pharm. 2010 Jul; 36(7):832-8.