"CD146 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule of the immunoglobulin superfamily that is expressed by ENDOTHELIAL CELLS where it functions to stabilize INTERCELLULAR JUNCTIONS. It is also highly expressed by melanoma tumor cells and may facilitate their METASTASIS.
| Descriptor ID |
D051929
|
| MeSH Number(s) |
D12.776.395.550.200.170 D12.776.543.550.200.140 D12.776.624.301.249 D23.050.285.439.249 D23.050.301.350.150
|
| Concept/Terms |
CD146 Antigen- CD146 Antigen
- Antigen, CD146
- S-Endo 1 Endothelial-Associated Antigen
- Melanoma Cell Adhesion Molecule
- CD146 Antigens
- Antigens, CD146
- Gicerin
- Glycoprotein MUC18
- MUC18, Glycoprotein
|
Below are MeSH descriptors whose meaning is more general than "CD146 Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD146 Antigen".
This graph shows the total number of publications written about "CD146 Antigen" by people in this website by year, and whether "CD146 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD146 Antigen" by people in Profiles.
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Circulating endothelial progenitors are increased in COVID-19 patients and correlate with SARS-CoV-2 RNA in severe cases. J Thromb Haemost. 2020 10; 18(10):2744-2750.
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Soluble CD146 and B-type natriuretic peptide dissect overhydration into functional components of prognostic relevance in haemodialysis patients. Nephrol Dial Transplant. 2018 11 01; 33(11):2035-2042.
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Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J Biol Chem. 2017 05 19; 292(20):8381-8389.
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The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis. Oncotarget. 2017 Feb 28; 8(9):15520-15538.
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Promoter methylation of MCAM, ERa and ERß in serum of early stage prostate cancer patients. Oncotarget. 2017 Feb 28; 8(9):15431-15440.
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Soluble CD146 Is a Novel Marker of Systemic Congestion in Heart Failure Patients: An Experimental Mechanistic and Transcardiac Clinical Study. Clin Chem. 2017 Jan; 63(1):386-393.
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Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. Hepatology. 2015 Mar; 61(3):843-56.
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Involvement of gicerin, a cell adhesion molecule, in tracheal development and regeneration. Cell Growth Differ. 1996 Dec; 7(12):1761-7.