Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
"Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.
| Descriptor ID |
D064428
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| MeSH Number(s) |
D12.776.157.530.400.368 D12.776.543.550.450.476 D12.776.543.585.400.476
|
| Concept/Terms |
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Hyperpolarization Activated Cyclic Nucleotide Gated Channels
- Ih Cation Channels
- Cation Channels, Ih
- Channels, Ih Cation
- Hyperpolarization Cyclic-Nucleotide Gated Ion Channels
- Hyperpolarization Cyclic Nucleotide Gated Ion Channels
- I(h) Channels
- Hyperpolarization-Activated Cation Channel
- Cation Channel, Hyperpolarization-Activated
- Channel, Hyperpolarization-Activated Cation
- Hyperpolarization Activated Cation Channel
- HCN Pacemaker Channels
- Channels, HCN Pacemaker
- Pacemaker Channels, HCN
- I(h) Cation Channels
HCN4 Channel- HCN4 Channel
- Channel, HCN4
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4
HCN3 Channel- HCN3 Channel
- Channel, HCN3
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3
HCN1 Channel- HCN1 Channel
- Channel, HCN1
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1
HCN2 Channel- HCN2 Channel
- Channel, HCN2
- Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2
- Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2
- HCN2 Potassium Channel
- Channel, HCN2 Potassium
- Potassium Channel, HCN2
- Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2
- Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2
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Below are MeSH descriptors whose meaning is more general than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
Below are MeSH descriptors whose meaning is more specific than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
This graph shows the total number of publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in this website by year, and whether "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 3 | 0 | 3 |
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Below are the most recent publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in Profiles.
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Further insights into the molecular complexity of the human sinus node - The role of 'novel' transcription factors and microRNAs. Prog Biophys Mol Biol. 2021 11; 166:86-104.
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Effects of HCN Channels in the Rostral Ventrolateral Medulla Contribute to the Cardiovascular Effects of Propofol. Mol Pharmacol. 2018 11; 94(5):1280-1288.
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Dexmedetomidine relieves neuropathic pain by inhibiting hyperpolarization-activated cyclic nucleotide-gated currents in dorsal root ganglia neurons. Neuroreport. 2018 08 15; 29(12):1001-1006.
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A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Elife. 2018 06 20; 7.
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Biological therapies targeting arrhythmias: are cells and genes the answer? Expert Opin Biol Ther. 2018 03; 18(3):237-249.