"Cytochrome P-450 CYP1B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
| Descriptor ID |
D065633
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| MeSH Number(s) |
D08.244.453.005.500 D08.244.453.100.875 D08.811.682.690.708.170.010.500 D08.811.682.690.708.170.020.875 D12.776.422.220.453.010.500 D12.776.422.220.453.100.875
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| Concept/Terms |
Cytochrome P-450 CYP1B1- Cytochrome P-450 CYP1B1
- Cytochrome P 450 CYP1B1
- Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
- Cytochrome P4501B1
- Cytochrome P450 CYP1B1
- P450 CYP1B1, Cytochrome
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1B1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1B1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1B1" by people in this website by year, and whether "Cytochrome P-450 CYP1B1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1B1" by people in Profiles.
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Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium. Sci Rep. 2019 10 15; 9(1):14812.
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Cataract extraction in patients with primary congenital glaucoma. Eur J Ophthalmol. 2020 May; 30(3):525-532.
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Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. Clin Epigenetics. 2018 10 20; 10(1):126.
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Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1-mediated metabolism to the product 4' hydroxy tangeretin. Toxicol In Vitro. 2018 Aug; 50:274-284.
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Role of CYP1B1, p.E229K and p.R368H mutations among 120 families with sporadic juvenile onset open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol. 2018 Feb; 256(2):355-362.
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Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells. Food Chem Toxicol. 2017 Dec; 110:383-394.
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Angiopoietin receptor TEK interacts with CYP1B1 in primary congenital glaucoma. Hum Genet. 2017 08; 136(8):941-949.
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Goniodysgenesis variability and activity of CYP1B1 genotypes in primary congenital glaucoma. PLoS One. 2017; 12(4):e0176386.
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Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk. J Natl Cancer Inst. 2006 Sep 20; 98(18):1311-20.