Platelet Glycoprotein GPIIb-IIIa Complex
"Platelet Glycoprotein GPIIb-IIIa Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
| Descriptor ID |
D019039
|
| MeSH Number(s) |
D12.776.395.550.625.785 D12.776.543.550.625.785 D12.776.543.750.705.408.460.700 D12.776.543.750.705.675.784
|
| Concept/Terms |
Platelet Glycoprotein GPIIb-IIIa Complex- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Glycoprotein GPIIb IIIa Complex
- Glycoproteins IIb-IIIa
- Glycoproteins IIb IIIa
- Integrin alpha-IIb beta-3
- Integrin alpha IIb beta 3
- beta-3, Integrin alpha-IIb
- Integrin alphaIIbbeta3
- alphaIIbbeta3, Integrin
- GPIIb-IIIa Receptors
- GPIIb IIIa Receptors
- Receptors, GPIIb-IIIa
|
Below are MeSH descriptors whose meaning is more general than "Platelet Glycoprotein GPIIb-IIIa Complex".
Below are MeSH descriptors whose meaning is more specific than "Platelet Glycoprotein GPIIb-IIIa Complex".
This graph shows the total number of publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in this website by year, and whether "Platelet Glycoprotein GPIIb-IIIa Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 4 | 10 | 14 |
| 2018 | 5 | 6 | 11 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in Profiles.
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SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype. Cell Death Dis. 2021 01 05; 12(1):50.
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Favorable effect of glycoprotein IIbIIIa inhibitors among STEMI patients treated with primary PCI and incomplete ST resolution. Platelets. 2020; 31(1):48-54.
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Characteristics and outcomes of patients requiring bailout use of glycoprotein IIb/IIIa inhibitors for thrombotic complications of percutaneous coronary intervention: An analysis from the CHAMPION PHOENIX trial. Int J Cardiol. 2019 Mar 01; 278:217-222.
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Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis. Circulation. 2018 10 16; 138(16):1720-1735.
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Apolipoprotein A-IV binds aIIbß3 integrin and inhibits thrombosis. Nat Commun. 2018 09 06; 9(1):3608.
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Changes in Periprocedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006 and 2013 (from the British Cardiovascular Interventional Society). Am J Cardiol. 2018 09 15; 122(6):952-960.
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Influence of aflibercept on platelet activation profile. Exp Eye Res. 2018 10; 175:166-172.
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Activated Clotting Time to Guide Heparin Dosing in Non-ST-Segment-Elevation Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention and Treated With IIb/IIIa Inhibitors: Impact on Ischemic and Bleeding Outcomes: Insights From the TAO Trial. Circ Cardiovasc Interv. 2018 06; 11(6):e006084.
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The efficacy of early versus delayed P2Y12 inhibition in percutaneous coronary intervention for ST-elevation myocardial infarction: a systematic review and meta-analysis. EuroIntervention. 2018 05 20; 14(1):78-85.
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Bivalirudin or Heparin in Patients Undergoing Invasive Management of Acute Coronary Syndromes. J Am Coll Cardiol. 2018 03 20; 71(11):1231-1242.