p38 Mitogen-Activated Protein Kinases
"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
| Descriptor ID |
D048051
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.843 D12.644.360.450.835 D12.776.476.450.835
|
| Concept/Terms |
p38 Mitogen-Activated Protein Kinases- p38 Mitogen-Activated Protein Kinases
- p38 Mitogen Activated Protein Kinases
- p38 MAP Kinase
- MAP Kinase, p38
- p38 MAPK
- MAPK, p38
- p38 SAPK
- Mitogen-Activated Protein Kinase p38
- Mitogen Activated Protein Kinase p38
- p38 Protein Kinase
- Protein Kinase, p38
|
Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 2 | 3 | 5 |
| 2017 | 13 | 17 | 30 |
| 2018 | 14 | 9 | 23 |
| 2019 | 2 | 4 | 6 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.
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SARS-CoV-2 attenuates corticosteroid sensitivity by suppressing DUSP1 expression and activating p38 MAPK pathway. Eur J Pharmacol. 2021 Oct 05; 908:174374.
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Computational Identification of Potential Anti-Inflammatory Natural Compounds Targeting the p38 Mitogen-Activated Protein Kinase (MAPK): Implications for COVID-19-Induced Cytokine Storm. Biomolecules. 2021 04 29; 11(5).
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N-Glycosylated Ganoderma lucidum immunomodulatory protein improved anti-inflammatory activity via inhibition of the p38 MAPK pathway. Food Funct. 2021 Apr 26; 12(8):3393-3404.
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Identification of human immune cell subtypes most responsive to IL-1ß-induced inflammatory signaling using mass cytometry. Sci Signal. 2021 03 09; 14(673).
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The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 08 06; 182(3):685-712.e19.
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p38 MAPK inhibition: A promising therapeutic approach for COVID-19. J Mol Cell Cardiol. 2020 07; 144:63-65.
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Is nicotine exposure linked to cardiopulmonary vulnerability to COVID-19 in the general population? FEBS J. 2020 09; 287(17):3651-3655.
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Sirtuin2 enhances the tumoricidal function of liver natural killer cells in a mouse hepatocellular carcinoma model. Cancer Immunol Immunother. 2019 Jun; 68(6):961-971.
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Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signalling pathways. Vet Microbiol. 2019 May; 232:1-12.
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Role of TLR-4 in anti-ß2-glycoprotein I-induced activation of peritoneal macrophages and vascular endothelial cells in mice. Mol Med Rep. 2019 May; 19(5):4353-4363.