Cyclin-Dependent Kinase 2
"Cyclin-Dependent Kinase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
| Descriptor ID |
D051357
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.750 D12.644.360.250.323 D12.776.167.200.323 D12.776.476.250.323
|
| Concept/Terms |
Cyclin-Dependent Kinase 2- Cyclin-Dependent Kinase 2
- Cyclin Dependent Kinase 2
- Cdk2 Protein Kinase
- Cdc2-Related Protein Kinase
- Cdc2 Related Protein Kinase
- p33cdk2 Kinase
- CDK2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 2".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 2".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase 2" by people in this website by year, and whether "Cyclin-Dependent Kinase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase 2" by people in Profiles.
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Mechanism of Juglone-Induced Cell Cycle Arrest and Apoptosis in Ishikawa Human Endometrial Cancer Cells. J Agric Food Chem. 2019 Jul 03; 67(26):7378-7389.
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Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells. FEBS Lett. 2018 06; 592(11):1893-1904.
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Porcine epidemic diarrhea virus through p53-dependent pathway causes cell cycle arrest in the G0/G1 phase. Virus Res. 2018 07 15; 253:1-11.
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The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006 Apr 21; 281(16):10669-81.
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Murine coronavirus replication induces cell cycle arrest in G0/G1 phase. J Virol. 2004 Jun; 78(11):5658-69.