"Nelfinavir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
| Descriptor ID |
D019888
|
| MeSH Number(s) |
D03.633.100.531.520
|
| Concept/Terms |
Nelfinavir Mesylate- Nelfinavir Mesylate
- Mesylate, Nelfinavir
- Nelfinavir Monomethane Sulfonate
- Monomethane Sulfonate, Nelfinavir
- Sulfonate, Nelfinavir Monomethane
|
Below are MeSH descriptors whose meaning is more general than "Nelfinavir".
Below are MeSH descriptors whose meaning is more specific than "Nelfinavir".
This graph shows the total number of publications written about "Nelfinavir" by people in this website by year, and whether "Nelfinavir" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Nelfinavir" by people in Profiles.
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Endoplasmic reticulum stress and NF-kB activation in SARS-CoV-2 infected cells and their response to antiviral therapy. IUBMB Life. 2022 01; 74(1):93-100.
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Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nat Commun. 2021 06 03; 12(1):3309.
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A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization. Sci Rep. 2021 05 26; 11(1):11049.
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Efficacy and safety of nelfinavir in asymptomatic and mild COVID-19 patients: a structured summary of a study protocol for a multicenter, randomized controlled trial. Trials. 2021 Apr 28; 22(1):309.
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Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing. ACS Nano. 2021 01 26; 15(1):857-872.
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The potential effects of clinical antidiabetic agents on SARS-CoV-2. J Diabetes. 2021 Mar; 13(3):243-252.
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Effect of nelfinavir stereoisomers on coronavirus main protease: Molecular docking, molecular dynamics simulation and MM/GBSA study. J Mol Graph Model. 2021 03; 103:107803.
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Targeting the coronavirus SARS-CoV-2: computational insights into the mechanism of action of the protease inhibitors lopinavir, ritonavir and nelfinavir. Sci Rep. 2020 12 01; 10(1):20927.
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Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis. Pharmacol Rep. 2020 Dec; 72(6):1553-1561.
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Phytochemicals from Selective Plants Have Promising Potential against SARS-CoV-2: Investigation and Corroboration through Molecular Docking, MD Simulations, and Quantum Computations. Biomed Res Int. 2020; 2020:6237160.