"Emetine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
| Descriptor ID |
D004640
|
| MeSH Number(s) |
D03.132.316 D03.633.100.531.321
|
| Concept/Terms |
Emetine- Emetine
- Methylcephaeline
- Ipecine
|
Below are MeSH descriptors whose meaning is more general than "Emetine".
Below are MeSH descriptors whose meaning is more specific than "Emetine".
This graph shows the total number of publications written about "Emetine" by people in this website by year, and whether "Emetine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Emetine" by people in Profiles.
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Zinc supplementation augments the suppressive effects of repurposed NF-?B inhibitors on ACE2 expression in human lung cell lines. Life Sci. 2021 Sep 01; 280:119752.
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Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E. Antiviral Res. 2021 05; 189:105056.
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Natural Products Homoharringtonine and Emetine Alkaloids as SARS-CoV-2 Treatment Options. Curr Pharm Des. 2021; 27(32):3444-3453.
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Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. 2020 06 13; 12(6).
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Does lopinavir really inhibit SARS-CoV-2? Pharmacol Res. 2020 08; 158:104898.
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Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro. Antiviral Res. 2020 06; 178:104786.
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In Vitro Data of Current Therapies for SARS-CoV-2. Curr Med Chem. 2020; 27(27):4542-4548.
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High-Throughput Screening and Identification of Potent Broad-Spectrum Inhibitors of Coronaviruses. J Virol. 2019 06 15; 93(12).