"Deubiquitinating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that remove UBIQUITIN from a protein substrate, including POLYUBIQUITIN, or from other molecules.
Descriptor ID |
D000072017
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MeSH Number(s) |
D08.811.037
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Deubiquitinating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Deubiquitinating Enzymes".
This graph shows the total number of publications written about "Deubiquitinating Enzymes" by people in this website by year, and whether "Deubiquitinating Enzymes" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 2 | 3 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deubiquitinating Enzymes" by people in Profiles.
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Binding of SARS-CoV Covalent Non-Covalent Inhibitors to the SARS-CoV-2 Papain-Like Protease and Ovarian Tumor Domain Deubiquitinases. Biomolecules. 2021 05 28; 11(6).
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Losartan Inhibits SARS-CoV-2 Replication in Vitro. J Pharm Pharm Sci. 2021; 24:390-399.
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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature. 2020 11; 587(7835):657-662.
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Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease. ACS Infect Dis. 2020 08 14; 6(8):2099-2109.
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Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19. Int J Mol Sci. 2020 May 15; 21(10).
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Suppression of the Ubiquitin Pathway by Small Molecule Binding to Ubiquitin Enhances Doxorubicin Sensitivity of the Cancer Cells. Molecules. 2019 Mar 19; 24(6).
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Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018 02 01; 102(2):296-308.
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Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus. J Virol. 2017 12 01; 91(23).
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Transmissible Gastroenteritis Virus Papain-Like Protease 1 Antagonizes Production of Interferon-ß through Its Deubiquitinase Activity. Biomed Res Int. 2017; 2017:7089091.
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A Naturally Occurring Recombinant Enterovirus Expresses a Torovirus Deubiquitinase. J Virol. 2017 07 15; 91(14).