"Holoenzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalytically active enzymes that are formed by the combination of an apoenzyme (APOENZYMES) and its appropriate cofactors and prosthetic groups.
Descriptor ID |
D020035
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MeSH Number(s) |
D08.811.255
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Holoenzymes".
Below are MeSH descriptors whose meaning is more specific than "Holoenzymes".
This graph shows the total number of publications written about "Holoenzymes" by people in this website by year, and whether "Holoenzymes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 1 | 2 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Holoenzymes" by people in Profiles.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase. Biochem J. 2021 07 16; 478(13):2425-2443.
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Comparative protein structure network analysis on 3CLpro from SARS-CoV-1 and SARS-CoV-2. Proteins. 2021 09; 89(9):1216-1225.
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Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. Cell. 2020 09 17; 182(6):1560-1573.e13.
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The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges. Pharmacol Ther. 2020 09; 213:107579.
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Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism. Biochemistry. 2017 08 01; 56(30):3885-3888.
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Local protein kinase A action proceeds through intact holoenzymes. Science. 2017 06 23; 356(6344):1288-1293.