"Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
Descriptor ID |
D008025
|
MeSH Number(s) |
D08.811.464
|
Concept/Terms |
Ligases- Ligases
- Synthetases
- Synthetase
|
Below are MeSH descriptors whose meaning is more general than "Ligases".
Below are MeSH descriptors whose meaning is more specific than "Ligases".
This graph shows the total number of publications written about "Ligases" by people in this website by year, and whether "Ligases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2017 | 2 | 1 | 3 |
2018 | 3 | 1 | 4 |
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Below are the most recent publications written about "Ligases" by people in Profiles.
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Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins. Signal Transduct Target Ther. 2021 03 15; 6(1):123.
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Biosynthesis of medicinal tropane alkaloids in yeast. Nature. 2020 09; 585(7826):614-619.
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The group I GH3 family genes encoding JA-Ile synthetase act as positive regulator in the resistance of rice to Xanthomonas oryzae pv. oryzae. Biochem Biophys Res Commun. 2019 01 22; 508(4):1062-1066.
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Structure of Escherichia coli Arginyl-tRNA Synthetase in Complex with tRNAArg: Pivotal Role of the D-loop. J Mol Biol. 2018 05 25; 430(11):1590-1606.
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Nitrate Reductases Are Relocalized to the Nucleus by AtSIZ1 and Their Levels Are Negatively Regulated by COP1 and Ammonium. Int J Mol Sci. 2018 Apr 15; 19(4).
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Reflex testing of speckled cytoplasmic patterns observed in routine ANA HEp-2 indirect immunofluorescence with a multiplex anti-synthetase dot-blot assay: a multicentric pilot study. Immunol Res. 2018 02; 66(1):74-78.
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Immunotherapy Targeting Adenosine Synthase A Decreases Severity of Staphylococcus aureus Infection in Mouse Model. J Infect Dis. 2017 07 15; 216(2):245-253.
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Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nat Chem Biol. 2017 Aug; 13(8):845-849.
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Clinical follow-up predictors of disease pattern change in anti-Jo1 positive anti-synthetase syndrome: Results from a multicenter, international and retrospective study. Autoimmun Rev. 2017 Mar; 16(3):253-257.
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Sumoylation of hypoxia inducible factor-1a and its significance in cancer. Sci China Life Sci. 2014 Jul; 57(7):657-64.