"Cysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
| Descriptor ID |
D003545
|
| MeSH Number(s) |
D02.886.030.230 D02.886.489.155 D12.125.154.299 D12.125.166.230
|
| Concept/Terms |
Cysteine- Cysteine
- L-Cysteine
- L Cysteine
- Half-Cystine
- Half Cystine
|
Below are MeSH descriptors whose meaning is more general than "Cysteine".
Below are MeSH descriptors whose meaning is more specific than "Cysteine".
This graph shows the total number of publications written about "Cysteine" by people in this website by year, and whether "Cysteine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 7 | 8 | 15 |
| 2018 | 5 | 6 | 11 |
| 2019 | 5 | 4 | 9 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cysteine" by people in Profiles.
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S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity. J Biol Chem. 2021 10; 297(4):101112.
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Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors. Bioorg Med Chem Lett. 2021 10 15; 50:128333.
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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300. mBio. 2021 08 31; 12(4):e0209421.
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Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms. Int J Biol Macromol. 2021 Sep 30; 187:976-987.
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Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins. Mol Pharmacol. 2021 08; 100(2):155-169.
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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nat Commun. 2021 05 24; 12(1):3061.
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Docking-based virtual screening studies aiming at the covalent inhibition of SARS-CoV-2 MPro by targeting the cysteine 145. Comput Biol Chem. 2021 Jun; 92:107463.
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l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated Monocytes. J Am Coll Nutr. 2021 May-Jun; 40(4):327-332.
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Dynamic Network Modeling of Allosteric Interactions and Communication Pathways in the SARS-CoV-2 Spike Trimer Mutants: Differential Modulation of Conformational Landscapes and Signal Transmission via Cascades of Regulatory Switches. J Phys Chem B. 2021 01 28; 125(3):850-873.
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Proton-Coupled Conformational Activation of SARS Coronavirus Main Proteases and Opportunity for Designing Small-Molecule Broad-Spectrum Targeted Covalent Inhibitors. J Am Chem Soc. 2020 12 30; 142(52):21883-21890.