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UTHORS
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Leike Zhang
Institution
Wuhan institute of Virology
Address
Wuhan
Hubei
China
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Publication Timeline
COVID-19 publications
All Publications
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To see the data from both graphs as text,
click here
.
Year
Publications
2012
2
2013
1
2014
1
2015
3
2016
4
2017
4
2018
2
2019
1
2020
14
2021
17
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To return to the graphs,
click here
.
Publication Field Summary
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
Publication List
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Most Discussed
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Wang Q
,
Wang L
,
Zhang Y
,
Zhang X
,
Zhang L
,
Shang W
,
Bai F
. Probing the Allosteric Inhibition Mechanism of a Spike Protein Using Molecular Dynamics Simulations and Active Compound Identifications. J Med Chem. 2022 02 24; 65(4):2827-2835.
PMID:
34415156
.
Citations:
Fields:
Che
Chemistry
Wang Y
,
Zhu X
,
Jiang XM
,
Guo J
,
Fu Z
,
Zhou Z
,
Yang P
,
Guo H
,
Guo X
,
Liang G
,
Zeng P
,
Xiao G
,
Ma J
,
Yin X
,
Zhang LK
,
Yan C
,
Zhang CY
. Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients. Signal Transduct Target Ther. 2021 08 11; 6(1):300.
PMID:
34381015
.
Citations:
1
Translation:
Humans
Cells
Wang L
,
Wu Y
,
Yao S
,
Ge H
,
Zhu Y
,
Chen K
,
Chen WZ
,
Zhang Y
,
Zhu W
,
Wang HY
,
Guo Y
,
Ma PX
,
Ren PX
,
Zhang XL
,
Li HQ
,
Ali MA
,
Xu WQ
,
Jiang HL
,
Zhang LK
,
Zhu LL
,
Ye Y
,
Shang WJ
,
Bai F
. Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein. Acta Pharmacol Sin. 2021 Aug 04.
PMID:
34349236
.
Citations:
1
Fields:
Pha
Pharmacology
Wang Y
,
Fang S
,
Wu Y
,
Cheng X
,
Zhang LK
,
Shen XR
,
Li SQ
,
Xu JR
,
Shang WJ
,
Gao ZB
,
Xia BQ
. Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates. Acta Pharmacol Sin. 2021 Jul 22.
PMID:
34294887
.
Citations:
2
Fields:
Pha
Pharmacology
Su H
,
Yao S
,
Zhao W
,
Zhang Y
,
Liu J
,
Shao Q
,
Wang Q
,
Li M
,
Xie H
,
Shang W
,
Ke C
,
Feng L
,
Jiang X
,
Shen J
,
Xiao G
,
Jiang H
,
Zhang L
,
Ye Y
,
Xu Y
. Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease. Nat Commun. 2021 06 15; 12(1):3623.
PMID:
34131140
.
Citations:
7
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Xia B
,
Shen X
,
He Y
,
Pan X
,
Liu FL
,
Wang Y
,
Yang F
,
Fang S
,
Wu Y
,
Duan Z
,
Zuo X
,
Xie Z
,
Jiang X
,
Xu L
,
Chi H
,
Li S
,
Meng Q
,
Zhou H
,
Zhou Y
,
Cheng X
,
Xin X
,
Jin L
,
Zhang HL
,
Yu DD
,
Li MH
,
Feng XL
,
Chen J
,
Jiang H
,
Xiao G
,
Zheng YT
,
Zhang LK
,
Shen J
,
Li J
,
Gao Z
. SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target. Cell Res. 2021 08; 31(8):847-860.
PMID:
34112954
.
Citations:
10
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Wang Z
,
Zhao Y
,
Wang Q
,
Xing Y
,
Feng L
,
Kong J
,
Peng C
,
Zhang L
,
Yang H
,
Lu M
. Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro. Signal Transduct Target Ther. 2021 06 01; 6(1):214.
PMID:
34075025
.
Citations:
1
Translation:
Humans
Animals
Amporndanai K
,
Meng X
,
Shang W
,
Jin Z
,
Rogers M
,
Zhao Y
,
Rao Z
,
Liu ZJ
,
Yang H
,
Zhang L
,
O'Neill PM
,
Samar Hasnain S
. Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nat Commun. 2021 05 24; 12(1):3061.
PMID:
34031399
.
Citations:
8
Fields:
Bio
Biology
Sci
Science
Translation:
Cells
Wang Q
,
Luo Y
,
Shang W
,
Shi Z
,
Xiao G
,
Zhang L
. Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus. Biosaf Health. 2021 Jun; 3(3):156-163.
PMID:
34027383
.
Citations:
Zhang LK
,
Sun Y
,
Zeng H
,
Wang Q
,
Jiang X
,
Shang WJ
,
Wu Y
,
Li S
,
Zhang YL
,
Hao ZN
,
Chen H
,
Jin R
,
Liu W
,
Li H
,
Peng K
,
Xiao G
. Author Correction: Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension. Cell Discov. 2021 May 03; 7(1):29.
PMID:
33941764
.
Citations:
1
Ren PX
,
Shang WJ
,
Yin WC
,
Ge H
,
Wang L
,
Zhang XL
,
Li BQ
, Li HL,
Xu YC
,
Xu EH
,
Jiang HL
,
Zhu LL
,
Zhang LK
,
Bai F
. A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors. Acta Pharmacol Sin. 2022 Feb; 43(2):483-493.
PMID:
33907306
.
Citations:
2
Fields:
Pha
Pharmacology
Dai W
,
Jochmans D
,
Xie H
,
Yang H
,
Li J
,
Su H
,
Chang D
,
Wang J
,
Peng J
,
Zhu L
,
Nian Y
,
Hilgenfeld R
,
Jiang H
,
Chen K
,
Zhang L
,
Xu Y
,
Neyts J
,
Liu H
. Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J Med Chem. 2022 02 24; 65(4):2794-2808.
PMID:
33872498
.
Citations:
2
Fields:
Che
Chemistry
Zhao Y
,
Du X
,
Duan Y
,
Pan X
,
Sun Y
,
You T
,
Han L
,
Jin Z
,
Shang W
,
Yu J
,
Guo H
,
Liu Q
,
Wu Y
,
Peng C
,
Wang J
,
Zhu C
,
Yang X
,
Yang K
,
Lei Y
,
Guddat LW
,
Xu W
,
Xiao G
,
Sun L
,
Zhang L
,
Rao Z
,
Yang H
. High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell. 2021 11; 12(11):877-888.
PMID:
33864621
.
Citations:
6
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Cells
Yin W
,
Luan X
,
Li Z
,
Zhou Z
,
Wang Q
,
Gao M
,
Wang X
,
Zhou F
,
Shi J
,
You E
,
Liu M
,
Wang Q
,
Jiang Y
,
Jiang H
,
Xiao G
,
Zhang L
,
Yu X
,
Zhang S
,
Eric Xu H
. Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin. Nat Struct Mol Biol. 2021 03; 28(3):319-325.
PMID:
33674802
.
Citations:
12
Fields:
Mol
Molecular Biology
Translation:
Animals
Cells
Zeng HL
,
Lu QB
,
Yang Q
,
Wang X
,
Yue DY
,
Zhang LK
,
Li H
,
Liu W
,
Li HJ
. Longitudinal Profile of Laboratory Parameters and Their Application in the Prediction for Fatal Outcome Among Patients Infected With SARS-CoV-2: A Retrospective Cohort Study. Clin Infect Dis. 2021 02 16; 72(4):626-633.
PMID:
33048116
.
Citations:
2
Fields:
Com
Communicable Diseases
Translation:
Humans
Wu J
,
Shi Y
,
Pan X
,
Wu S
,
Hou R
,
Zhang Y
,
Zhong T
,
Tang H
,
Du W
,
Wang L
,
Wo J
,
Mu J
,
Qiu Y
,
Yang K
,
Zhang LK
,
Ye BC
,
Qi N
. SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO. Cell Rep. 2021 02 16; 34(7):108761.
PMID:
33567255
.
Citations:
31
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Xiong R
,
Zhang L
,
Li S
,
Sun Y
,
Ding M
,
Wang Y
,
Zhao Y
,
Wu Y
,
Shang W
,
Jiang X
,
Shan J
,
Shen Z
,
Tong Y
,
Xu L
,
Chen Y
,
Liu Y
,
Zou G
,
Lavillete D
,
Zhao Z
,
Wang R
,
Zhu L
,
Xiao G
,
Lan K
, Li H,
Xu K
. Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein Cell. 2021 Jan; 12(1):76-80.
PMID:
33029721
.
Citations:
Fields:
Bio
Biochemistry
Cel
Cell Biology
Zhang LK
,
Sun Y
,
Zeng H
,
Wang Q
,
Jiang X
,
Shang WJ
,
Wu Y
,
Li S
,
Zhang YL
,
Hao ZN
,
Chen H
,
Jin R
,
Liu W
,
Li H
,
Peng K
,
Xiao G
. Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension. Cell Discov. 2020 Dec 22; 6(1):96.
PMID:
33349633
.
Citations:
23
Wan W
,
Zhu S
,
Li S
,
Shang W
,
Zhang R
,
Li H
,
Liu W
,
Xiao G
,
Peng K
,
Zhang L
. High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-2. ACS Infect Dis. 2021 06 11; 7(6):1409-1422.
PMID:
33183004
.
Citations:
8
Fields:
Ant
Anti-Infective Agents
Dru
Drug Therapy
Mic
Microbiology
Translation:
Humans
Xiong R
,
Zhang L
,
Li S
,
Sun Y
,
Ding M
,
Wang Y
,
Zhao Y
,
Wu Y
,
Shang W
,
Jiang X
,
Shan J
,
Shen Z
,
Tong Y
,
Xu L
,
Chen Y
,
Liu Y
,
Zou G
,
Lavillette D
,
Zhao Z
,
Wang R
,
Zhu L
,
Xiao G
,
Lan K
, Li H,
Xu K
. Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein Cell. 2020 Nov 09.
PMID:
33165830
.
Citations:
1
Fields:
Bio
Biochemistry
Cel
Cell Biology
Zhou Z
,
Zhou Y
,
Jiang XM
,
Wang Y
,
Chen X
,
Xiao G
,
Zhang CY
,
Yi Y
,
Zhang LK
,
Li L
. Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication. Cell Discov. 2020; 6:63.
PMID:
32934821
.
Citations:
4
Zhang L
,
Liu J
,
Cao R
,
Xu M
,
Wu Y
,
Shang W
,
Wang X
,
Zhang H
,
Jiang X
,
Sun Y
,
Hu H
,
Li Y
,
Zou G
,
Zhang M
,
Zhao L
,
Li W
,
Guo X
,
Zhuang X
,
Yang XL
,
Shi ZL
,
Deng F
,
Hu Z
,
Xiao G
,
Wang M
,
Zhong W
. Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro. Virol Sin. 2020 Dec; 35(6):776-784.
PMID:
32910347
.
Citations:
6
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Zhou LK
,
Zhou Z
,
Jiang XM
,
Zheng Y
,
Chen X
,
Fu Z
,
Xiao G
,
Zhang CY
,
Zhang LK
,
Yi Y
. Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients. Cell Discov. 2020; 6(1):54.
PMID:
32802404
.
Citations:
18
Xiong R
,
Zhang L
,
Li S
,
Sun Y
,
Ding M
,
Wang Y
,
Zhao Y
,
Wu Y
,
Shang W
,
Jiang X
,
Shan J
,
Shen Z
,
Tong Y
,
Xu L
,
Chen Y
,
Liu Y
,
Zou G
,
Lavillete D
,
Zhao Z
,
Wang R
,
Zhu L
,
Xiao G
,
Lan K
, Li H,
Xu K
. Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein Cell. 2020 10; 11(10):723-739.
PMID:
32754890
.
Citations:
28
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Animals
Cells
PH
Public Health
Su HX
,
Yao S
,
Zhao WF
,
Li MJ
,
Liu J
,
Shang WJ
,
Xie H
,
Ke CQ
,
Hu HC
,
Gao MN
,
Yu KQ
,
Liu H
,
Shen JS
,
Tang W
,
Zhang LK
,
Xiao GF
,
Ni L
,
Wang DW
,
Zuo JP
,
Jiang HL
,
Bai F
,
Wu Y
,
Ye Y
,
Xu YC
. Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients. Acta Pharmacol Sin. 2020 Sep; 41(9):1167-1177.
PMID:
32737471
.
Citations:
79
Fields:
Pha
Pharmacology
Translation:
Humans
Animals
Cells
PH
Public Health
Lu QB
,
Jiang WL
,
Zhang X
,
Li HJ
,
Zhang XA
,
Zeng HL
,
Du J
,
Yang GL
,
Zhang LK
,
Li R
,
Fang LQ
,
Li H
,
Liu W
. Comorbidities for fatal outcome among the COVID-19 patients: A hospital-based case-control study. J Infect. 2021 01; 82(1):159-198.
PMID:
32731000
.
Citations:
5
Fields:
Com
Communicable Diseases
Translation:
Humans
Jin Z
,
Zhao Y
,
Sun Y
,
Zhang B
,
Wang H
,
Wu Y
,
Zhu Y
,
Zhu C
,
Hu T
,
Du X
,
Duan Y
,
Yu J
,
Yang X
,
Yang X
,
Yang K
,
Liu X
,
Guddat LW
,
Xiao G
,
Zhang L
,
Yang H
,
Rao Z
. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nat Struct Mol Biol. 2020 06; 27(6):529-532.
PMID:
32382072
.
Citations:
103
Fields:
Mol
Molecular Biology
Translation:
Animals
Cells
PH
Public Health
Dai W
,
Zhang B
,
Jiang XM
,
Su H
,
Li J
,
Zhao Y
,
Xie X
,
Jin Z
,
Peng J
,
Liu F
,
Li C
,
Li Y
,
Bai F
,
Wang H
,
Cheng X
,
Cen X
,
Hu S
,
Yang X
,
Wang J
,
Liu X
,
Xiao G
,
Jiang H
,
Rao Z
,
Zhang LK
,
Xu Y
,
Yang H
,
Liu H
. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science. 2020 06 19; 368(6497):1331-1335.
PMID:
32321856
.
Citations:
335
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
PH
Public Health
Mu J
,
Xu J
,
Zhang L
,
Shu T
,
Wu D
,
Huang M
,
Ren Y
,
Li X
,
Geng Q
,
Xu Y
,
Qiu Y
,
Zhou X
. SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells. Sci China Life Sci. 2020 09; 63(9):1413-1416.
PMID:
32291557
.
Citations:
34
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
PH
Public Health
Jin Z
,
Du X
,
Xu Y
,
Deng Y
,
Liu M
,
Zhao Y
,
Zhang B
,
Li X
,
Zhang L
,
Peng C
,
Duan Y
,
Yu J
,
Wang L
,
Yang K
,
Liu F
,
Jiang R
,
Yang X
,
You T
,
Liu X
,
Yang X
,
Bai F
,
Liu H
,
Liu X
,
Guddat LW
,
Xu W
,
Xiao G
,
Qin C
,
Shi Z
,
Jiang H
,
Rao Z
,
Yang H
. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors. Nature. 2020 06; 582(7811):289-293.
PMID:
32272481
.
Citations:
758
Fields:
Sci
Science
Translation:
Humans
Cells
PH
Public Health
Wang M
,
Cao R
,
Zhang L
,
Yang X
,
Liu J
,
Xu M
,
Shi Z
,
Hu Z
,
Zhong W
,
Xiao G
. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 03; 30(3):269-271.
PMID:
32020029
.
Citations:
2312
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Bernstein LR
,
Zhang L
. Gallium maltolate has in vitro antiviral activity against SARS-CoV-2 and is a potential treatment for COVID-19. Antivir Chem Chemother. 2020 Jan-Dec; 28:2040206620983780.
PMID:
33353394
.
Citations:
1
Fields:
Ant
Anti-Infective Agents
Che
Chemistry
Vir
Virology
Translation:
Animals
Cells
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Concepts (201)
Derived automatically from this person's publications.
Pyrones
Insect Proteins
Organometallic Compounds
Sendai virus
Respirovirus Infections
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Xiao, Gengfu
Wang, Qingxing
Shang, Weijuan
Zhong, Wu
Wan, Weiwei
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