"Complement C4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.
| Descriptor ID |
D003181
|
| MeSH Number(s) |
D12.776.124.486.274.350
|
| Concept/Terms |
Complement C4- Complement C4
- C4, Complement
- Complement Component 4
- Component 4, Complement
- Complement 4
- C4 Complement
- Complement, C4
- C4 Complement Component
- Complement Component, C4
- Component, C4 Complement
|
Below are MeSH descriptors whose meaning is more general than "Complement C4".
Below are MeSH descriptors whose meaning is more specific than "Complement C4".
This graph shows the total number of publications written about "Complement C4" by people in this website by year, and whether "Complement C4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 5 | 8 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Complement C4" by people in Profiles.
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Serum Complement C3 and C4 and COVID-19 Severity and Mortality: A Systematic Review and Meta-Analysis With Meta-Regression. Front Immunol. 2021; 12:696085.
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Broad auto-reactive IgM responses are common in critically ill patients, including those with COVID-19. Cell Rep Med. 2021 06 15; 2(6):100321.
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C-Reactive Protein Triggers Cell Death in Ischemic Cells. Front Immunol. 2021; 12:630430.
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Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID-19 patients. Eur J Immunol. 2021 03; 51(3):634-647.
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Concomitant new diagnosis of systemic lupus erythematosus and COVID-19 with possible antiphospholipid syndrome. Just a coincidence? A case report and review of intertwining pathophysiology. Clin Rheumatol. 2020 Sep; 39(9):2811-2815.
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Contribution of acute-phase reaction proteins to the diagnosis and treatment of 2019 novel coronavirus disease (COVID-19). Epidemiol Infect. 2020 07 27; 148:e164.
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Is there relationship between SARS-CoV-2 and the complement C3 and C4? Turk J Med Sci. 2020 06 23; 50(4):687-688.
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SARS-CoV-2-Induced Immune Dysregulation and Myocardial Injury Risk in China: Insights From the ERS-COVID-19 Study. Circ Res. 2020 07 17; 127(3):397-399.
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COVID-19 and Acute Lupus Pneumonitis: Diagnostic and Treatment Dilemma. J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620933438.
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Blood Cell-Bound C4d as a Marker of Complement Activation in Patients With the Antiphospholipid Syndrome. Front Immunol. 2019; 10:773.