"Complement Factor B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
| Descriptor ID |
D011415
|
| MeSH Number(s) |
D08.622.200 D08.811.277.656.300.760.198 D08.811.277.656.959.350.198 D12.776.124.486.274.900
|
| Concept/Terms |
Complement Factor B- Complement Factor B
- Factor B, Complement
- C3 Proactivator
- Proactivator, C3
- C3PA
- Complement 3 Proactivator
- Proactivator, Complement 3
- Factor B
- Complement Protein B
- Protein B, Complement
- Complement Protein Factor B
- Properdin Factor B
- Factor B, Properdin
- Complement Factor B, Alternative Pathway
Complement Factor Bb- Complement Factor Bb
- Bb, Complement Factor
- Factor Bb, Complement
- Properdin Factor Bb
- Factor Bb, Properdin
- Complement Factor B-Derived Fragment Bb
- Complement Factor B Derived Fragment Bb
- Bb Fragment of Factor B
- Complement Factor B Fragment, Bb
Complement Factor Ba- Complement Factor Ba
- Factor Ba, Complement
- Properdin Factor Ba
- Factor Ba, Properdin
|
Below are MeSH descriptors whose meaning is more general than "Complement Factor B".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor B".
This graph shows the total number of publications written about "Complement Factor B" by people in this website by year, and whether "Complement Factor B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement Factor B" by people in Profiles.
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SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol. 2021 04 07; 6(58).
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Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis. J Immunol. 2019 10 01; 203(7):1973-1980.
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The utility of complement assays in clinical immunology: A comprehensive review. J Autoimmun. 2018 12; 95:191-200.
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Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population. Br J Ophthalmol. 2018 12; 102(12):1691-1695.
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Immobilization Strategies for Functional Complement Convertase Assembly at Lipid Membrane Interfaces. Langmuir. 2017 07 25; 33(29):7332-7342.
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Anti-Factor B and Anti-C3b Autoantibodies in C3 Glomerulopathy and Ig-Associated Membranoproliferative GN. J Am Soc Nephrol. 2017 May; 28(5):1603-1613.