"Connexin 26" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gap junction protein encoded by the Gap Junction Beta 2 or GJB2 gene. In the cochlea and epidermis, its hexamers form channels between cells that open to allow cell-to-cell diffusion of small molecules as well as recycling of potassium. Mutations in Connexin 26 are associated with congenital SENSORINEURAL HEARING LOSS.
| Descriptor ID |
D000072259
|
| MeSH Number(s) |
D12.776.543.585.250.100
|
| Concept/Terms |
Connexin 26- Connexin 26
- 26, Connexin
- beta2 Connexin
- Connexin, beta2
- Connexin beta-2
- Connexin beta 2
- beta-2, Connexin
- Connexin Cx26
- Cx26, Connexin
|
Below are MeSH descriptors whose meaning is more general than "Connexin 26".
Below are MeSH descriptors whose meaning is more specific than "Connexin 26".
This graph shows the total number of publications written about "Connexin 26" by people in this website by year, and whether "Connexin 26" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Connexin 26" by people in Profiles.
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Keratoderma-Deafness-Mucocutaneous Syndrome Associated with Phe142Leu in the GJB2 Gene. Acta Derm Venereol. 2019 Nov 01; 99(12):1192-1194.
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Russian 'CRISPR-baby' scientist has started editing genes in human eggs with goal of altering deaf gene. Nature. 2019 10; 574(7779):465-466.
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Spectrum of GJB2 gene variants in Indian children with non-syndromic hearing loss. Indian J Med Res. 2018 06; 147(6):615-618.
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Association between the p.V37I variant of GJB2 and hearing loss: a pedigree and meta-analysis. Oncotarget. 2017 Jul 11; 8(28):46681-46690.
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Congenital Cytomegalovirus Infection and Permanent Hearing Loss in Rural North Indian Children. Pediatr Infect Dis J. 2017 07; 36(7):670-673.
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Identification of a novel homozygous mutation in transmembrane channel like 1 (TMC1) gene, one of the second-tier hearing loss genes after GJB2 in India. Indian J Med Res. 2017 Apr; 145(4):492-497.
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Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment. Sci China Life Sci. 2015 Sep; 58(9):829-38.