"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
|
| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 2 | 3 |
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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A method to probe protein structure from UV absorbance spectra. Anal Biochem. 2019 12 15; 587:113450.
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Enhanced Ability of Oligomeric Nanobodies Targeting MERS Coronavirus Receptor-Binding Domain. Viruses. 2019 02 19; 11(2).
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In Reference to Saliva Pepsin Detection and Proton Pump Inhibitor Response in Suspected Laryngopharyngeal Reflux. Laryngoscope. 2019 04; 129(4):E118-E119.
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Drugs of porcine origin-A risk for patients with a-gal syndrome? J Allergy Clin Immunol Pract. 2019 May - Jun; 7(5):1687-1690.e3.
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Is Pepsin a Reliable Marker of Laryngopharyngeal Reflux? A Systematic Review. Otolaryngol Head Neck Surg. 2017 09; 157(3):385-391.
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Impact of tapered-cuff tracheal tube on microaspiration of gastric contents in intubated critically ill patients: a multicenter cluster-randomized cross-over controlled trial. Intensive Care Med. 2017 Nov; 43(11):1562-1571.
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Microaspiration in intubated critically ill patients: diagnosis and prevention. Infect Disord Drug Targets. 2011 Aug; 11(4):413-23.
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Detecting the other reflux disease. J Fam Pract. 2010 Feb; 59(2):102-7.
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Characterization of intrinsic and extrinsic risk factors for celery allergy in immunosenescence. Mech Ageing Dev. 2008 Mar; 129(3):120-8.
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Stability of porcine colostral immunoglobulins IgA, IgA2, and IgM to proteolytic enzymes. Am J Vet Res. 1979 May; 40(5):607-12.