"Peptide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
| Descriptor ID |
D010447
|
| MeSH Number(s) |
D08.811.277.656
|
| Concept/Terms |
Peptide Hydrolases- Peptide Hydrolases
- Proteolytic Enzymes
- Proteases
- Proteinases
- Esteroproteases
- Peptidases
|
Below are MeSH descriptors whose meaning is more general than "Peptide Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Peptide Hydrolases".
This graph shows the total number of publications written about "Peptide Hydrolases" by people in this website by year, and whether "Peptide Hydrolases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 1 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 5 | 0 | 5 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 4 | 0 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 2 | 5 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 6 | 11 | 17 |
| 2018 | 10 | 8 | 18 |
| 2019 | 3 | 0 | 3 |
| 2020 | 4 | 10 | 14 |
| 2021 | 8 | 14 | 22 |
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Below are the most recent publications written about "Peptide Hydrolases" by people in Profiles.
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Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):1646-1650.
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Interactions of Ozone-Functionalized Activated Charcoal with SARS-Cov-2 Proteases Using Molecular Docking and Dynamics. J Nanosci Nanotechnol. 2021 12 01; 21(12):6060-6072.
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A Combined Molecular Docking and Density Functional Theory Nuclear Magnetic Resonance Study of Trans-Dehydrocrotonin Interacting with COVID-19 Main Protease and Severe Acute Respiratory Syndrome Coronavirus 2 3C-Like Protease. J Nanosci Nanotechnol. 2021 11 01; 21(11):5399-5407.
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Inhibitor potency and assay conditions: A case study on SARS-CoV-2 main protease. Proc Natl Acad Sci U S A. 2021 09 07; 118(36).
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Reply to Behnam and Klein: Potential role of the His-tag in C-terminal His-tagged SARS-CoV-2 main protease. Proc Natl Acad Sci U S A. 2021 09 07; 118(36).
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Cellular host factors for SARS-CoV-2 infection. Nat Microbiol. 2021 10; 6(10):1219-1232.
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Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease. ACS Infect Dis. 2021 09 10; 7(9):2591-2595.
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Discovery of Novel Small-Molecule Inhibitors of SARS-CoV-2 Main Protease as Potential Leads for COVID-19 Treatment. J Chem Inf Model. 2021 09 27; 61(9):4745-4757.
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Dinitrosyl iron complexes (DNICs) as inhibitors of the SARS-CoV-2 main protease. Chem Commun (Camb). 2021 Aug 28; 57(67):8352-8355.
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Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19. Comput Biol Med. 2021 09; 136:104686.