Macrophage Colony-Stimulating Factor
"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
Descriptor ID |
D016173
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MeSH Number(s) |
D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
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Concept/Terms |
Macrophage Colony-Stimulating Factor- Macrophage Colony-Stimulating Factor
- M-CSF
- CSF-1
- CSF-M
- Colony-Stimulating Factor 1
- Colony Stimulating Factor 1
- Colony-Stimulating Factor, Macrophage
- Colony Stimulating Factor, Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 1 | 2 | 3 |
2018 | 3 | 3 | 6 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.
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Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M-CSF- and IL-34-differentiated macrophages in vitro. Biochem Biophys Res Commun. 2021 03 26; 546:97-102.
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Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation, innate immunity hyperactivation, and organ damage in COVID-19 pneumonia. Cytokine. 2021 04; 140:155438.
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Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2. Elife. 2021 01 14; 10.
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Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. Front Immunol. 2018; 9:2303.
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Endothelial-to-mesenchymal transition shapes the atherosclerotic plaque and modulates macrophage function. FASEB J. 2019 02; 33(2):2278-2289.
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Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells. Cell Death Dis. 2018 09 20; 9(10):968.
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Recent advances in colony stimulating factor-1 receptor/c-FMS as an emerging target for various therapeutic implications. Biomed Pharmacother. 2018 Jul; 103:662-679.
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Muscularis macrophage development in the absence of an enteric nervous system. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):4696-4701.
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Dynamic changes in hippocampal microglia contribute to depressive-like behavior induced by early social isolation. Neuropharmacology. 2018 06; 135:223-233.
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PLEKHO2 is essential for M-CSF-dependent macrophage survival. Cell Signal. 2017 09; 37:115-122.