"Succinate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
| Descriptor ID |
D013385
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| MeSH Number(s) |
D05.500.562.750.249.500 D08.811.600.250.500.750.500 D08.811.600.250.875.249.500 D08.811.682.660.385.500 D08.811.682.830.249.500 D12.776.157.427.374.375.909.500 D12.776.331.199.750.500 D12.776.543.277.500.750.500 D12.776.543.277.875.249.500 D12.776.556.579.374.375.141.500
|
| Concept/Terms |
Succinate Dehydrogenase- Succinate Dehydrogenase
- Dehydrogenase, Succinate
- Succinic Dehydrogenase
- Dehydrogenase, Succinic
- Succinic Oxidase
- Oxidase, Succinic
- Fumarate Reductase
- Reductase, Fumarate
|
Below are MeSH descriptors whose meaning is more general than "Succinate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate Dehydrogenase".
This graph shows the total number of publications written about "Succinate Dehydrogenase" by people in this website by year, and whether "Succinate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Succinate Dehydrogenase" by people in Profiles.
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Synthesis of N,N'-bis(1,5-dimethyl-2-phenyl-1,2-dihydro-3-oxopyrazol-4-yl) sebacamide that ameliorate osteoarthritis symptoms and improve bone marrow matrix structure and cartilage alterations induced by monoiodoacetate in the rat model: "Suggested potent anti-inflammatory agent against COVID-19". Hum Exp Toxicol. 2021 Feb; 40(2):325-341.
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Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report. Diagn Pathol. 2019 May 15; 14(1):42.
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SDH2 is involved in proper hypha formation and virulence in Candida albicans. Future Microbiol. 2018 08; 13:1141-1156.
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A Duodenal SDH-Deficient Gastrointestinal Stromal Tumor in a Patient With a Germline SDHB Mutation. J Clin Endocrinol Metab. 2017 05 01; 102(5):1447-1450.
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Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1. Cell Rep. 2017 01 17; 18(3):659-672.
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Magnetic resonance spectroscopy of paragangliomas: new insights into in vivo metabolomics. Endocr Relat Cancer. 2015 Aug; 22(4):M1-8.
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Succinate dehydrogenase gene mutations in cardiac paragangliomas. Am J Cardiol. 2015 Jun 15; 115(12):1753-9.
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Mitochondrial complex II participates in normoxic and hypoxic regulation of a-keto acids in the murine heart. J Mol Cell Cardiol. 2010 Dec; 49(6):950-61.
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Local-regional recurrence of sporadic or syndromic abdominal extra-adrenal paraganglioma: incidence, characteristics, and outcome. Surgery. 2009 Dec; 146(6):986-92.
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Histochemical demonstration of changes in liver cell enzymes in pregnant mice infected with Coxsackie B3 virus. Histochemistry. 1974; 40(2):175-80.