Aphasia, Primary Progressive
"Aphasia, Primary Progressive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
| Descriptor ID |
D018888
|
| MeSH Number(s) |
C10.228.140.380.132 C10.597.606.150.500.800.100.155 C23.888.592.604.150.500.800.100.155 F03.615.400.125
|
| Concept/Terms |
Aphasia, Primary Progressive- Aphasia, Primary Progressive
- Aphasias, Primary Progressive
- Primary Progressive Aphasia
- Primary Progressive Aphasias
- Progressive Aphasia, Primary
- Progressive Aphasias, Primary
- Mesulam's Syndrome
- Syndrome, Mesulam's
- Mesulam Syndrome
- Syndrome, Mesulam
|
Below are MeSH descriptors whose meaning is more general than "Aphasia, Primary Progressive".
Below are MeSH descriptors whose meaning is more specific than "Aphasia, Primary Progressive".
This graph shows the total number of publications written about "Aphasia, Primary Progressive" by people in this website by year, and whether "Aphasia, Primary Progressive" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Aphasia, Primary Progressive" by people in Profiles.
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Machine learning in the clinical and language characterisation of primary progressive aphasia variants. Cortex. 2019 10; 119:312-323.
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Crossed aphasia confirmed by fMRI in a case with nonfluent variant of primary progressive aphasia carrying a GRN mutation. J Neurol. 2019 May; 266(5):1274-1279.
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Plasma Neurofilament Light Chain in Primary Progressive Aphasia and Related Disorders: Clinical Significance and Metabolic Correlates. J Alzheimers Dis. 2019; 72(3):773-782.
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Mendelian forms of disease and age at onset affect survival in frontotemporal dementia. Amyotroph Lateral Scler Frontotemporal Degener. 2018 02; 19(1-2):87-92.
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Typical and atypical pathology in primary progressive aphasia variants. Ann Neurol. 2017 Mar; 81(3):430-443.
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Frontotemporal Dementia due to the Novel GRN Arg161GlyfsX36 Mutation. J Alzheimers Dis. 2017; 57(4):1185-1189.
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GBA-associated parkinsonism and dementia: beyond a-synucleinopathies? Eur J Neurol. 2016 Mar; 23(3):520-6.