Frontotemporal Lobar Degeneration
"Frontotemporal Lobar Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
Descriptor ID |
D057174
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MeSH Number(s) |
C10.228.140.380.266 C10.574.950.300 C18.452.845.800.300 F03.615.400.380
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Concept/Terms |
Frontotemporal Lobar Degeneration- Frontotemporal Lobar Degeneration
- Degeneration, Frontotemporal Lobar
- Degenerations, Frontotemporal Lobar
- Frontotemporal Lobar Degenerations
- Lobar Degeneration, Frontotemporal
- Lobar Degenerations, Frontotemporal
- FTLD
- FTLDs
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Below are MeSH descriptors whose meaning is more general than "Frontotemporal Lobar Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Frontotemporal Lobar Degeneration".
This graph shows the total number of publications written about "Frontotemporal Lobar Degeneration" by people in this website by year, and whether "Frontotemporal Lobar Degeneration" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2017 | 4 | 0 | 4 |
2018 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frontotemporal Lobar Degeneration" by people in Profiles.
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Telemedicine for Delivery of Care in Frontotemporal Lobar Degeneration During COVID-19 Pandemic: Results from Southern Italy. J Alzheimers Dis. 2020; 76(2):481-489.
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Disease-modifying therapies for tauopathies: agents in the pipeline. Expert Rev Neurother. 2019 05; 19(5):397-408.
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Serum C-Peptide, Visfatin, Resistin, and Ghrelin are Altered in Sporadic and GRN-Associated Frontotemporal Lobar Degeneration. J Alzheimers Dis. 2018; 61(3):1053-1060.
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PCSK9 Concentrations in Cerebrospinal Fluid Are Not Specifically Increased in Alzheimer's Disease. J Alzheimers Dis. 2018; 62(4):1519-1525.
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The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Autophagy. 2017; 13(12):2115-2162.
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Neurodegeneration of brain networks in the amyotrophic lateral sclerosis-frontotemporal lobar degeneration (ALS-FTLD) continuum: evidence from MRI and MEG studies. CNS Spectr. 2018 12; 23(6):378-387.
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Frontotemporal lobar degeneration and social behaviour: Dissociation between the knowledge of its consequences and its conceptual meaning. Cortex. 2017 08; 93:107-118.
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Typical and atypical pathology in primary progressive aphasia variants. Ann Neurol. 2017 Mar; 81(3):430-443.
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Understanding phenotype variability in frontotemporal lobar degeneration due to granulin mutation. Neurobiol Aging. 2014 May; 35(5):1206-11.
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PGRN mutations in northern Italy. Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):301-2.