Tissue Inhibitor of Metalloproteinases
"Tissue Inhibitor of Metalloproteinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.
| Descriptor ID |
D019714
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| MeSH Number(s) |
D12.776.645.875
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinases".
Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinases".
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinases" by people in this website by year, and whether "Tissue Inhibitor of Metalloproteinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinases" by people in Profiles.
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Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells. Free Radic Biol Med. 2019 04; 134:516-526.
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Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS). PLoS Negl Trop Dis. 2018 08; 12(8):e0006710.
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Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice. Cardiovasc Diabetol. 2018 07 26; 17(1):106.
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Nandrolone decanoate interferes with testosterone biosynthesis altering blood-testis barrier components. J Cell Mol Med. 2017 08; 21(8):1636-1647.
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Matrix metalloproteinase dysregulation in HIV infection: implications for therapeutic strategies. Trends Mol Med. 2007 Nov; 13(11):449-59.
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Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. J Virol. 2005 Apr; 79(8):4764-73.
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Regulation of matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) genes during JHMV infection of the central nervous system. Adv Exp Med Biol. 2001; 494:329-34.