Protein Synthesis Inhibitors
"Protein Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
| Descriptor ID |
D011500
|
| MeSH Number(s) |
D27.505.519.389.760
|
| Concept/Terms |
Protein Synthesis Inhibitors- Protein Synthesis Inhibitors
- Inhibitors, Protein Synthesis
- Protein Synthesis Antagonists
- Antagonists, Protein Synthesis
|
Below are MeSH descriptors whose meaning is more general than "Protein Synthesis Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Protein Synthesis Inhibitors".
This graph shows the total number of publications written about "Protein Synthesis Inhibitors" by people in this website by year, and whether "Protein Synthesis Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Protein Synthesis Inhibitors" by people in Profiles.
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A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry. Nat Commun. 2021 06 23; 12(1):3907.
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HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics. Virology. 2018 10; 523:27-34.
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Thrombin stimulates increased plasminogen activator inhibitor-1 release from liver compared to lung endothelium. J Surg Res. 2018 05; 225:1-5.
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Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme. Cell Death Dis. 2017 05 18; 8(5):e2807.
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Development and RNA-synthesizing activity of coronavirus replication structures in the absence of protein synthesis. J Virol. 2011 Jun; 85(11):5669-73.
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Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J. 2001 Apr 17; 20(8):1829-39.
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Subgenomic negative-strand RNA function during mouse hepatitis virus infection. J Virol. 2000 May; 74(9):4039-46.
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Equine arteritis virus subgenomic RNA transcription: UV inactivation and translation inhibition studies. Virology. 1995 Nov 10; 213(2):364-72.