Nucleic Acid Synthesis Inhibitors
"Nucleic Acid Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit cell production of DNA or RNA.
| Descriptor ID |
D019384
|
| MeSH Number(s) |
D27.505.519.389.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Synthesis Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Synthesis Inhibitors".
This graph shows the total number of publications written about "Nucleic Acid Synthesis Inhibitors" by people in this website by year, and whether "Nucleic Acid Synthesis Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 2 | 3 |
| 2020 | 2 | 1 | 3 |
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Below are the most recent publications written about "Nucleic Acid Synthesis Inhibitors" by people in Profiles.
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Antiviral drug discovery: preparing for the next pandemic. Chem Soc Rev. 2021 Mar 21; 50(6):3647-3655.
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RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19. Biochem Biophys Res Commun. 2021 01 29; 538:47-53.
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Advances and challenges in the prevention and treatment of COVID-19. Int J Med Sci. 2020; 17(12):1803-1810.
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Potential therapeutic targets and promising drugs for combating SARS-CoV-2. Br J Pharmacol. 2020 07; 177(14):3147-3161.
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Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children. Pediatr Infect Dis J. 2020 05; 39(5):355-368.
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Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study. Life Sci. 2020 Jul 15; 253:117592.
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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus. J Biol Chem. 2020 04 10; 295(15):4773-4779.
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Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors. J Virol. 2019 09 15; 93(18).
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Efficacy and safety of long-term therapy with nucleos(t)ide analogues in chronic hepatitis B. Ter Arkh. 2019 Mar 18; 91(2):40-47.
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Letermovir for prophylaxis of cytomegalovirus manifestations in adult allogeneic hematopoietic stem cell transplant recipients. Future Microbiol. 2019 02; 14:175-184.