"Receptors, Somatomedin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.
| Descriptor ID |
D017451
|
| MeSH Number(s) |
D12.776.543.750.750.400.780
|
| Concept/Terms |
Receptors, Somatomedin- Receptors, Somatomedin
- Insulin-Like Growth Factor Receptors
- Insulin Like Growth Factor Receptors
- Somatomedin Receptor
- Receptor, Somatomedin
- Somatomedin Receptors
- Insulin-Like Growth Factor Receptor
- Insulin Like Growth Factor Receptor
- Receptors, Insulin-Like Growth Factors
- Receptors, Insulin Like Growth Factors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatomedin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatomedin".
This graph shows the total number of publications written about "Receptors, Somatomedin" by people in this website by year, and whether "Receptors, Somatomedin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 3 | 6 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Somatomedin" by people in Profiles.
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Serum antibodies against the insulin-like growth factor-1 receptor (IGF-1R) in Graves' disease and Graves' orbitopathy. J Endocrinol Invest. 2019 Apr; 42(4):471-480.
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Rotavirus-encoded virus-like small RNA triggers autophagy by targeting IGF1R via the PI3K/Akt/mTOR pathway. Biochim Biophys Acta Mol Basis Dis. 2018 Jan; 1864(1):60-68.
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CKS1BP7, a Pseudogene of CKS1B, is Co-Amplified with IGF1R in Breast Cancers. Pathol Oncol Res. 2018 Apr; 24(2):223-229.
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Expressions of insulin-like growth factor receptor-1 and cezanne-1 in lung adenocarcinoma. Med Oncol. 2017 May; 34(5):78.
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Cruel fusion: What a young man's death means for childhood cancer. Nature. 2017 03 28; 543(7647):608-611.
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miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. Genes Dev. 2017 03 15; 31(6):553-566.
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Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling. Sci Rep. 2017 03 14; 7:44473.