Receptors, Platelet-Derived Growth Factor
"Receptors, Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
| Descriptor ID |
D017479
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900 D12.776.543.750.630.625 D12.776.543.750.750.400.630
|
| Concept/Terms |
Receptors, Platelet-Derived Growth Factor- Receptors, Platelet-Derived Growth Factor
- Receptors, Platelet Derived Growth Factor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- Receptors, PDGF
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Receptors, Platelet-Derived Growth Factor" by people in this website by year, and whether "Receptors, Platelet-Derived Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Platelet-Derived Growth Factor" by people in Profiles.
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Targeting Hedgehog signaling pathway: Paving the road for cancer therapy. Pharmacol Res. 2019 03; 141:466-480.
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PDGF in organ fibrosis. Mol Aspects Med. 2018 08; 62:44-62.
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Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion. Neuroscience. 2017 Nov 19; 364:202-211.
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SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models. Acta Pharmacol Sin. 2018 Feb; 39(2):243-250.
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Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma. BMC Cancer. 2012 Dec 10; 12:587.
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Pazopanib for the treatment of renal cancer. Expert Opin Pharmacother. 2011 May; 12(7):1171-89.
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Quantitative functional imaging by dynamic contrast enhanced ultrasonography (DCE-US) in GIST patients treated with masatinib. Invest New Drugs. 2012 Apr; 30(2):765-71.
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The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex. J Cell Biol. 1994 Dec; 127(6 Pt 2):1843-57.