"1-Deoxynojirimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
| Descriptor ID |
D017485
|
| MeSH Number(s) |
D02.491.567.500.033 D03.132.014 D03.383.621.300.033 D09.553.500.033
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "1-Deoxynojirimycin".
Below are MeSH descriptors whose meaning is more specific than "1-Deoxynojirimycin".
This graph shows the total number of publications written about "1-Deoxynojirimycin" by people in this website by year, and whether "1-Deoxynojirimycin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
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Below are the most recent publications written about "1-Deoxynojirimycin" by people in Profiles.
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The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication. Glycobiology. 2021 05 03; 31(4):378-384.
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Inhibitors of Protein Glycosylation Are Active against the Coronavirus Severe Acute Respiratory Syndrome Coronavirus SARS-CoV-2. Viruses. 2021 04 30; 13(5).
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Identification of a novel loss-of-function mutation of the GLA gene in a Chinese Han family with Fabry disease. BMC Med Genet. 2018 12 27; 19(1):219.
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Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ). Adv Protein Chem Struct Biol. 2019; 114:341-407.
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Interaction of antidiabetic a-glucosidase inhibitors and gut bacteria a-glucosidase. Protein Sci. 2018 08; 27(8):1498-1508.
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Metabolic Effect of 1-Deoxynojirimycin from Mulberry Leaves on db/db Diabetic Mice Using Liquid Chromatography-Mass Spectrometry Based Metabolomics. J Agric Food Chem. 2017 Jun 14; 65(23):4658-4667.
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N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery. AIDS. 2008 Oct 01; 22(15):1961-9.
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The effects of processing inhibitors of N-linked oligosaccharides on the intracellular migration of glycoprotein E2 of mouse hepatitis virus and the maturation of coronavirus particles. J Biol Chem. 1985 Dec 15; 260(29):15873-9.