Low Density Lipoprotein Receptor-Related Protein-2
"Low Density Lipoprotein Receptor-Related Protein-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.
| Descriptor ID |
D026561
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| MeSH Number(s) |
D12.776.526.200 D12.776.543.750.710.450.500.200 D23.050.422.500.500
|
| Concept/Terms |
Low Density Lipoprotein Receptor-Related Protein-2- Low Density Lipoprotein Receptor-Related Protein-2
- Low Density Lipoprotein Receptor Related Protein 2
- LDL-Receptor Related Protein 2
- LDL Receptor Related Protein 2
- Low-Density Lipoprotein Receptor-Related Protein-2
- LRP-2 Receptor
- LRP 2 Receptor
- Megalin
- Heyman's Nephritis Antigen GP330
- Renal Glycoprotein GP330
- GP330, Renal Glycoprotein
- Glycoprotein GP330, Renal
- Antigen GP 330, Nephritis
- Glycoprotein 330
- GP330 Antigen
- Heymann Nephritis Antigen GP330
- Nephritis Antigen (GP330)
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Below are MeSH descriptors whose meaning is more general than "Low Density Lipoprotein Receptor-Related Protein-2".
Below are MeSH descriptors whose meaning is more specific than "Low Density Lipoprotein Receptor-Related Protein-2".
This graph shows the total number of publications written about "Low Density Lipoprotein Receptor-Related Protein-2" by people in this website by year, and whether "Low Density Lipoprotein Receptor-Related Protein-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 2 | 3 |
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Below are the most recent publications written about "Low Density Lipoprotein Receptor-Related Protein-2" by people in Profiles.
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Hypercalciuria and nephrolithiasis: Expanding the renal phenotype of Donnai-Barrow syndrome. Clin Genet. 2018 07; 94(1):187-188.
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Podocytes are new cellular targets of haemoglobin-mediated renal damage. J Pathol. 2018 03; 244(3):296-310.
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Decreased expression of megalin and cubilin and altered mitochondrial activity in tenofovir nephrotoxicity. Hum Pathol. 2018 03; 73:89-101.
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LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease. J Am Soc Nephrol. 2018 02; 29(2):644-653.
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Albumin uptake in human podocytes: a possible role for the cubilin-amnionless (CUBAM) complex. Sci Rep. 2017 10 20; 7(1):13705.
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V-ATPase/mTOR signaling regulates megalin-mediated apical endocytosis. Cell Rep. 2014 Jul 10; 8(1):10-9.