"Motor Neuron Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Descriptor ID |
D016472
|
| MeSH Number(s) |
C10.574.562 C10.668.467
|
| Concept/Terms |
Motor Neuron Disease- Motor Neuron Disease
- Motor Neuron Diseases
- Neuron Disease, Motor
- Neuron Diseases, Motor
- Motor System Disease
- Motor System Diseases
Lateral Sclerosis- Lateral Sclerosis
- Lateral Scleroses
- Scleroses, Lateral
- Sclerosis, Lateral
- Primary Lateral Sclerosis
- Lateral Scleroses, Primary
- Lateral Sclerosis, Primary
- Primary Lateral Scleroses
- Scleroses, Primary Lateral
- Sclerosis, Primary Lateral
|
Below are MeSH descriptors whose meaning is more general than "Motor Neuron Disease".
Below are MeSH descriptors whose meaning is more specific than "Motor Neuron Disease".
This graph shows the total number of publications written about "Motor Neuron Disease" by people in this website by year, and whether "Motor Neuron Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 2 | 0 | 2 |
| 2017 | 6 | 1 | 7 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Motor Neuron Disease" by people in Profiles.
-
Presentation of motor neuron disease in a patient with weight loss and acute-on-chronic respiratory failure. BMJ Case Rep. 2021 Apr 21; 14(4).
-
Curious case of steroid responsive diffuse anterior horn cell disease associated with COVID-19 infection. Neurol Sci. 2021 Aug; 42(8):3415-3417.
-
Anti-HMGCR myopathy misdiagnosed as motor neuron disease and complicated with COVID-19 infection. Neurol Sci. 2021 05; 42(5):1679-1682.
-
The immediate impact of the COVID-19 pandemic on motor neuron disease services and mortality in Scotland. J Neurol. 2021 Jun; 268(6):2038-2040.
-
Central nervous system abnormalities in spinal and bulbar muscular atrophy (Kennedy's disease). Clin Neurol Neurosurg. 2019 Sep; 184:105426.
-
Communicating psychosocial well-being in motor neurone disease to staff: results from a World Café approach. Qual Life Res. 2019 Sep; 28(9):2579-2584.
-
Brain MRI shows white matter sparing in Kennedy's disease and slow-progressing lower motor neuron disease. Hum Brain Mapp. 2019 07; 40(10):3102-3112.
-
Cerebrospinal Fluid Neurofilaments May Discriminate Upper Motor Neuron Syndromes: A Pilot Study. Neurodegener Dis. 2018; 18(5-6):255-261.
-
Provincial Differences in the Diagnosis and Care of Amyotrophic Lateral Sclerosis. Can J Neurol Sci. 2018 11; 45(6):652-659.
-
Cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: A two-centre tract of interest-based DTI analysis. Neuroimage Clin. 2018; 20:1062-1069.