"Tauopathies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Descriptor ID |
D024801
|
| MeSH Number(s) |
C10.574.945
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tauopathies".
Below are MeSH descriptors whose meaning is more specific than "Tauopathies".
This graph shows the total number of publications written about "Tauopathies" by people in this website by year, and whether "Tauopathies" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tauopathies" by people in Profiles.
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Editorial: Targets for Disease-Modifying Therapies in Alzheimer's Disease, Including Amyloid ß and Tau Protein. Med Sci Monit. 2021 Jul 26; 27:e934077.
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Could SARS-CoV-2 cause tauopathy? Lancet Neurol. 2021 07; 20(7):506.
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Neuroinflammation and Not Tauopathy Is a Predominant Pathological Signature of Nodding Syndrome. J Neuropathol Exp Neurol. 2019 11 01; 78(11):1049-1058.
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Disease-modifying therapies for tauopathies: agents in the pipeline. Expert Rev Neurother. 2019 05; 19(5):397-408.
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Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy. Lab Invest. 2019 07; 99(7):1019-1029.
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A new MAPT deletion in a case of speech apraxia leading to corticobasal syndrome. Neurocase. 2018 06; 24(3):140-144.
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SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy. J Neurosci. 2018 04 11; 38(15):3680-3688.
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Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease. Hum Mol Genet. 2018 01 01; 27(1):30-40.
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Bin1 directly remodels actin dynamics through its BAR domain. EMBO Rep. 2017 11; 18(11):2051-2066.
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Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biol. 2017 Jun; 15(6):e2001336.