"PrPC Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
| Descriptor ID |
D018621
|
| MeSH Number(s) |
D12.776.785.340.500
|
| Concept/Terms |
PrPC Proteins- PrPC Proteins
- PrP-sen
- PrP sen
- Cp 33-35
- Scrapie Amyloid Precursor Protein
- Cp33-35, Scrapie
|
Below are MeSH descriptors whose meaning is more general than "PrPC Proteins".
Below are MeSH descriptors whose meaning is more specific than "PrPC Proteins".
This graph shows the total number of publications written about "PrPC Proteins" by people in this website by year, and whether "PrPC Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "PrPC Proteins" by people in Profiles.
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Prion protein is essential for diabetic retinopathy-associated neovascularization. Angiogenesis. 2018 11; 21(4):767-775.
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Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease. PLoS One. 2018; 13(5):e0197659.
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Bovine PrPC directly interacts with alphaB-crystalline. FEBS Lett. 2005 Oct 10; 579(24):5419-24.