"Cathelicidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes.
Descriptor ID |
D054804
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MeSH Number(s) |
D12.644.050.099 D12.776.543.695.054.099
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cathelicidins".
Below are MeSH descriptors whose meaning is more specific than "Cathelicidins".
This graph shows the total number of publications written about "Cathelicidins" by people in this website by year, and whether "Cathelicidins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 1 | 0 | 1 |
2017 | 4 | 0 | 4 |
2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Cathelicidins" by people in Profiles.
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Antimicrobial peptides and other peptide-like therapeutics as promising candidates to combat SARS-CoV-2. Expert Rev Anti Infect Ther. 2021 10; 19(10):1205-1217.
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Bioinformatic Analysis of Genome-Predicted Bat Cathelicidins. Molecules. 2021 Mar 23; 26(6).
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Mast cells as protectors of health. J Allergy Clin Immunol. 2019 10; 144(4S):S4-S18.
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Roles of polymorphic cathelicidins in innate immunity of soft-shell turtle, Pelodiscus sinensis. Dev Comp Immunol. 2019 03; 92:179-192.
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Python Cathelicidin CATHPb1 Protects against Multidrug-Resistant Staphylococcal Infections by Antimicrobial-Immunomodulatory Duality. J Med Chem. 2018 03 08; 61(5):2075-2086.
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Significance and Diagnostic Role of Antimicrobial Cathelicidins (LL-37) Peptides in Oral Health. Biomolecules. 2017 12 05; 7(4).
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As-CATH4 and 5, two vertebrate-derived natural host defense peptides, enhance the immuno-resistance efficiency against bacterial infections in Chinese mitten crab, Eriocheir sinensis. Fish Shellfish Immunol. 2017 Dec; 71:202-209.
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Antimicrobial cathelicidin peptide LL-37 induces NET formation and suppresses the inflammatory response in a mouse septic model. Mol Med Rep. 2017 Oct; 16(4):5618-5626.
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Cathelicidin-trypsin inhibitor loop conjugate represents a promising antibiotic candidate with protease stability. Sci Rep. 2017 06 01; 7(1):2600.
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Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Cytokine. 2011 Aug; 55(2):294-300.