"Ketones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds containing a carbonyl group =C=O bonded to two hydrocarbon groups.
| Descriptor ID |
D007659
|
| MeSH Number(s) |
D02.522
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ketones".
Below are MeSH descriptors whose meaning is more specific than "Ketones".
This graph shows the total number of publications written about "Ketones" by people in this website by year, and whether "Ketones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 2 | 2 | 4 |
| 2018 | 4 | 0 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ketones" by people in Profiles.
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Polyketone metabolites isolated from Rhodiola tibetica endohytic fungus Alternaria sp. HJT-Y7 and their SARS-CoV-2 virus inhibitory activitives. Bioorg Chem. 2021 11; 116:105309.
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Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLpro). J Med Chem. 2022 02 24; 65(4):2880-2904.
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3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J Med Chem. 2022 02 24; 65(4):2926-2939.
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Field-Template, QSAR, Ensemble Molecular Docking, and 3D-RISM Solvation Studies Expose Potential of FDA-Approved Marine Drugs as SARS-CoVID-2 Main Protease Inhibitors. Molecules. 2021 Feb 10; 26(4).
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A new class of a-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities. Eur J Med Chem. 2021 Apr 05; 215:113267.
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Pseudo-Dipeptide Bearing a,a-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses. Int J Mol Sci. 2021 Jan 30; 22(3).
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The dark side of the spoon - glucose, ketones and COVID-19: a possible role for ketogenic diet? J Transl Med. 2020 11 20; 18(1):441.
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Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 11 12; 63(21):12725-12747.
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COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm. Oxid Med Cell Longev. 2020; 2020:6401341.
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Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2*. Chembiochem. 2020 12 01; 21(23):3383-3388.