"Organoselenium Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain selenium as an integral part of the molecule.
| Descriptor ID |
D016566
|
| MeSH Number(s) |
D02.712
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Organoselenium Compounds".
Below are MeSH descriptors whose meaning is more specific than "Organoselenium Compounds".
This graph shows the total number of publications written about "Organoselenium Compounds" by people in this website by year, and whether "Organoselenium Compounds" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 4 | 0 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Organoselenium Compounds" by people in Profiles.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease. Biochem J. 2021 07 16; 478(13):2499-2515.
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Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation. Molecules. 2021 Jul 12; 26(14).
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Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins. Mol Pharmacol. 2021 08; 100(2):155-169.
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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nat Commun. 2021 05 24; 12(1):3061.
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In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabolites and Derivatives. Mol Inform. 2021 08; 40(8):e2100028.
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Ebsulfur and Ebselen as highly potent scaffolds for the development of potential SARS-CoV-2 antivirals. Bioorg Chem. 2021 07; 112:104889.
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Toxicology and pharmacology of synthetic organoselenium compounds: an update. Arch Toxicol. 2021 04; 95(4):1179-1226.
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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2. Sci Rep. 2021 02 11; 11(1):3640.
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Therapeutic approaches against coronaviruses acute respiratory syndrome. Pharmacol Res Perspect. 2021 02; 9(1):e00691.
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Ebselen, a new candidate therapeutic against SARS-CoV-2. Int J Surg. 2020 12; 84:53-56.