"NF-E2-Related Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
| Descriptor ID |
D051267
|
| MeSH Number(s) |
D12.776.260.108.737 D12.776.930.127.737
|
| Concept/Terms |
NF-E2-Related Factor 2- NF-E2-Related Factor 2
- NF E2 Related Factor 2
- Nuclear Factor E2-Related Factor 2
- Nuclear Factor E2 Related Factor 2
- Nfe2l2 Protein
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NF-E2-Related Factor 2".
Below are MeSH descriptors whose meaning is more specific than "NF-E2-Related Factor 2".
This graph shows the total number of publications written about "NF-E2-Related Factor 2" by people in this website by year, and whether "NF-E2-Related Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 22 | 12 | 34 |
| 2018 | 21 | 18 | 39 |
| 2019 | 8 | 6 | 14 |
| 2020 | 1 | 4 | 5 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "NF-E2-Related Factor 2" by people in Profiles.
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Management of COVID-19-induced ?cytokine ?storm by Keap1-Nrf2 system: a? r?eview. Inflammopharmacology. 2021 Oct; 29(5):1347-1355.
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Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology. Mech Ageing Dev. 2021 10; 199:111551.
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The Good and Bad of Nrf2: An Update in Cancer and New Perspectives in COVID-19. Int J Mol Sci. 2021 Jul 26; 22(15).
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Low-dose radiation therapy (LDRT) for COVID-19 and its deadlier variants. Arch Toxicol. 2021 10; 95(10):3425-3432.
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Homeostatic control of redox status and health. IUBMB Life. 2022 01; 74(1):24-28.
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Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism. Front Immunol. 2021; 12:653110.
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Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury. World J Gastroenterol. 2021 Jun 14; 27(22):2944-2962.
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Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 05 29; 6(1):212.
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Nrf2 activator PB125® as a carnosic acid-based therapeutic agent against respiratory viral diseases, including COVID-19. Free Radic Biol Med. 2021 11 01; 175:56-64.
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Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4. Immunopharmacol Immunotoxicol. 2021 Jun; 43(3):309-318.