Interferon Regulatory Factor-1
"Interferon Regulatory Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
| Descriptor ID |
D050856
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| MeSH Number(s) |
D12.644.360.024.302.124 D12.776.157.057.050.124 D12.776.260.108.374 D12.776.260.504.124 D12.776.476.024.385.124 D12.776.930.127.374 D12.776.930.332.124
|
| Concept/Terms |
Interferon Regulatory Factor-1- Interferon Regulatory Factor-1
- Interferon Regulatory Factor 1
- IRF-1 Protein
- IRF 1 Protein
- IREBF1 Transcription Factor
- Transcription Factor, IREBF1
- IREBF1 Protein
- IRF-1 Transcription Factor
- Factor, IRF-1 Transcription
- IRF 1 Transcription Factor
- Transcription Factor, IRF-1
- ISGF1 Transcription Factor
- Factor, ISGF1 Transcription
- Transcription Factor, ISGF1
- Interferon-Stimulated Gene Factor 1
- Interferon Stimulated Gene Factor 1
- MyD32 Protein
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-1".
This graph shows the total number of publications written about "Interferon Regulatory Factor-1" by people in this website by year, and whether "Interferon Regulatory Factor-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Interferon Regulatory Factor-1" by people in Profiles.
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Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-? in vitro and in mice. Eur Respir J. 2020 Nov; 56(5).
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Interferon gamma inhibits transmissible gastroenteritis virus infection mediated by an IRF1 signaling pathway. Arch Virol. 2019 Nov; 164(11):2659-2669.
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Interferon regulatory factor 1 eliminates mycobacteria by suppressing p70 S6 kinase via mechanistic target of rapamycin signaling. J Infect. 2019 09; 79(3):262-276.
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Interferon Regulatory Factors 1 and 2 Play Different Roles in MHC II Expression Mediated by CIITA in Grass Carp, Ctenopharyngodon idella. Front Immunol. 2019; 10:1106.
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The Eukaryotic Translation Initiation Factor 4F Complex Restricts Rotavirus Infection via Regulating the Expression of IRF1 and IRF7. Int J Mol Sci. 2019 Mar 29; 20(7).
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Nitazoxanide Inhibits Human Norovirus Replication and Synergizes with Ribavirin by Activation of Cellular Antiviral Response. Antimicrob Agents Chemother. 2018 11; 62(11).
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IRF-1, RIG-I and MDA5 display potent antiviral activities against norovirus coordinately induced by different types of interferons. Antiviral Res. 2018 07; 155:48-59.
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Type III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling. J Virol. 2018 02 15; 92(4).
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Interferon regulatory factor 1 is essential for pathogenic CD8+ T cell migration and retention in the brain during experimental cerebral malaria. Cell Microbiol. 2018 05; 20(5):e12819.
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An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses. Cell Rep. 2017 Nov 07; 21(6):1600-1612.