"Fos-Related Antigen-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-leucine zipper transcription factor that is closely related to C-FOS PROTEINS. It forms heterodimeric complexes with C-JUN PROTEINS to regulate GENE transcription.
Descriptor ID |
D051921
|
MeSH Number(s) |
D12.776.260.108.311 D12.776.930.127.311
|
Concept/Terms |
Fos-Related Antigen-2- Fos-Related Antigen-2
- Fos Related Antigen 2
- Fra-2 Transcription Factor
- Transcription Factor, Fra-2
|
Below are MeSH descriptors whose meaning is more general than "Fos-Related Antigen-2".
Below are MeSH descriptors whose meaning is more specific than "Fos-Related Antigen-2".
This graph shows the total number of publications written about "Fos-Related Antigen-2" by people in this website by year, and whether "Fos-Related Antigen-2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2017 | 1 | 2 | 3 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fos-Related Antigen-2" by people in Profiles.
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Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin. Mol Cell Biol. 2018 11 15; 38(22).
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Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis. Arthritis Rheumatol. 2017 11; 69(11):2209-2221.
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Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis. Ann Rheum Dis. 2017 Nov; 76(11):1941-1948.
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Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription. J Exp Med. 2017 Jul 03; 214(7):2059-2071.
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Overexpression of Fos-related antigen-1 in head and neck squamous cell carcinoma. Int J Exp Pathol. 2005 Aug; 86(4):205-12.